Improving long-term renal allograft survival via a road less traveled by

M. D. Stegall, W. D. Park, P. G. Dean, F. G. Cosio

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

It has become cliché to state that improvements in early renal allograft survival over the past two decades have not led to increased long-term renal allograft survival. However, it is not clear how long-term graft survival can be improved. Here, we present the viewpoint that the road forward does not involve searching for new and more ideal immunosuppressive regimens, but rather detailed patient follow-up to identify specific causes of late renal allograft loss and the development of new therapy designed to address these problems before allograft damage becomes irreversible.

Original languageEnglish (US)
Pages (from-to)1382-1387
Number of pages6
JournalAmerican Journal of Transplantation
Volume11
Issue number7
DOIs
StatePublished - Jul 2011

Keywords

  • Allograft nephropathy
  • chronic rejection
  • immunosuppressive therapy
  • kidney transplantation
  • long-term graft survival

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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