Improvement of Shear Wave Motion Detection Using Harmonic Imaging in Healthy Human Liver

Carolina Amador, Pengfei Song, Duane D. Meixner, Shigao D Chen, Matthew W Urban

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Quantification of liver elasticity is a major application of shear wave elasticity imaging (SWEI) to non-invasive assessment of liver fibrosis stages. SWEI measurements can be highly affected by ultrasound image quality. Ultrasound harmonic imaging has exhibited a significant improvement in ultrasound image quality as well as for SWEI measurements. This was previously illustrated in cardiac SWEI. The purpose of this study was to evaluate liver shear wave particle displacement detection and shear wave velocity (SWV) measurements with fundamental and filter-based harmonic ultrasound imaging. In a cohort of 17 patients with no history of liver disease, a 2.9-fold increase in maximum shear wave displacement, a 0.11 m/s decrease in the overall interquartile range and median SWV and a 17.6% increase in the success rate of SWV measurements were obtained when filter-based harmonic imaging was used instead of fundamental imaging.

Original languageEnglish (US)
JournalUltrasound in Medicine and Biology
DOIs
StateAccepted/In press - Oct 12 2015

Fingerprint

Elasticity
liver
S waves
harmonics
Liver
elastic properties
Ultrasonography
velocity measurement
Liver Cirrhosis
Liver Diseases
filters
fibrosis
histories

Keywords

  • Filter-based harmonic imaging
  • In vivo
  • Liver elasticity
  • Shear wave elasticity imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Biophysics

Cite this

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title = "Improvement of Shear Wave Motion Detection Using Harmonic Imaging in Healthy Human Liver",
abstract = "Quantification of liver elasticity is a major application of shear wave elasticity imaging (SWEI) to non-invasive assessment of liver fibrosis stages. SWEI measurements can be highly affected by ultrasound image quality. Ultrasound harmonic imaging has exhibited a significant improvement in ultrasound image quality as well as for SWEI measurements. This was previously illustrated in cardiac SWEI. The purpose of this study was to evaluate liver shear wave particle displacement detection and shear wave velocity (SWV) measurements with fundamental and filter-based harmonic ultrasound imaging. In a cohort of 17 patients with no history of liver disease, a 2.9-fold increase in maximum shear wave displacement, a 0.11 m/s decrease in the overall interquartile range and median SWV and a 17.6{\%} increase in the success rate of SWV measurements were obtained when filter-based harmonic imaging was used instead of fundamental imaging.",
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AU - Song, Pengfei

AU - Meixner, Duane D.

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AU - Urban, Matthew W

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AB - Quantification of liver elasticity is a major application of shear wave elasticity imaging (SWEI) to non-invasive assessment of liver fibrosis stages. SWEI measurements can be highly affected by ultrasound image quality. Ultrasound harmonic imaging has exhibited a significant improvement in ultrasound image quality as well as for SWEI measurements. This was previously illustrated in cardiac SWEI. The purpose of this study was to evaluate liver shear wave particle displacement detection and shear wave velocity (SWV) measurements with fundamental and filter-based harmonic ultrasound imaging. In a cohort of 17 patients with no history of liver disease, a 2.9-fold increase in maximum shear wave displacement, a 0.11 m/s decrease in the overall interquartile range and median SWV and a 17.6% increase in the success rate of SWV measurements were obtained when filter-based harmonic imaging was used instead of fundamental imaging.

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