Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy

R. Alan Wright, J. Desmond O'Duffy, Moses Rodriguez

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

The authors present a patient with Sjogren's syndrome with a fluctuating and then progressive myelopathic syndrome, and optic nerve involvement. Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided. Spinal MRI showed multiple, extensive intraparenchymal areas of abnormal T2-weighted signal intensity, gadolinium enhancement, and cord swelling, which also improved during the period of treatment.

Original languageEnglish (US)
Pages (from-to)386-388
Number of pages3
JournalNeurology
Volume52
Issue number2
DOIs
StatePublished - Jan 15 1999

ASJC Scopus subject areas

  • Clinical Neurology

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