Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy

R. Alan Wright, J. Desmond O'Duffy, Moses Rodriguez

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The authors present a patient with Sjogren's syndrome with a fluctuating and then progressive myelopathic syndrome, and optic nerve involvement. Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided. Spinal MRI showed multiple, extensive intraparenchymal areas of abnormal T2-weighted signal intensity, gadolinium enhancement, and cord swelling, which also improved during the period of treatment.

Original languageEnglish (US)
Pages (from-to)386-388
Number of pages3
JournalNeurology
Volume52
Issue number2
StatePublished - Jan 15 1999

Fingerprint

Chlorambucil
Spinal Cord Diseases
Sjogren's Syndrome
Prednisone
Wheelchairs
Gadolinium
Optic Nerve
Walking
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Wright, R. A., O'Duffy, J. D., & Rodriguez, M. (1999). Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy. Neurology, 52(2), 386-388.

Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy. / Wright, R. Alan; O'Duffy, J. Desmond; Rodriguez, Moses.

In: Neurology, Vol. 52, No. 2, 15.01.1999, p. 386-388.

Research output: Contribution to journalArticle

Wright, RA, O'Duffy, JD & Rodriguez, M 1999, 'Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy', Neurology, vol. 52, no. 2, pp. 386-388.
Wright RA, O'Duffy JD, Rodriguez M. Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy. Neurology. 1999 Jan 15;52(2):386-388.
Wright, R. Alan ; O'Duffy, J. Desmond ; Rodriguez, Moses. / Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy. In: Neurology. 1999 ; Vol. 52, No. 2. pp. 386-388.
@article{48ed854e8fc3453ba79a8072ed59cf1c,
title = "Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy",
abstract = "The authors present a patient with Sjogren's syndrome with a fluctuating and then progressive myelopathic syndrome, and optic nerve involvement. Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided. Spinal MRI showed multiple, extensive intraparenchymal areas of abnormal T2-weighted signal intensity, gadolinium enhancement, and cord swelling, which also improved during the period of treatment.",
author = "Wright, {R. Alan} and O'Duffy, {J. Desmond} and Moses Rodriguez",
year = "1999",
month = "1",
day = "15",
language = "English (US)",
volume = "52",
pages = "386--388",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Improvement of myelopathy in Sjogren's syndrome with chlorambucil and prednisone therapy

AU - Wright, R. Alan

AU - O'Duffy, J. Desmond

AU - Rodriguez, Moses

PY - 1999/1/15

Y1 - 1999/1/15

N2 - The authors present a patient with Sjogren's syndrome with a fluctuating and then progressive myelopathic syndrome, and optic nerve involvement. Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided. Spinal MRI showed multiple, extensive intraparenchymal areas of abnormal T2-weighted signal intensity, gadolinium enhancement, and cord swelling, which also improved during the period of treatment.

AB - The authors present a patient with Sjogren's syndrome with a fluctuating and then progressive myelopathic syndrome, and optic nerve involvement. Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided. Spinal MRI showed multiple, extensive intraparenchymal areas of abnormal T2-weighted signal intensity, gadolinium enhancement, and cord swelling, which also improved during the period of treatment.

UR - http://www.scopus.com/inward/record.url?scp=0033554881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033554881&partnerID=8YFLogxK

M3 - Article

C2 - 9932962

AN - SCOPUS:0033554881

VL - 52

SP - 386

EP - 388

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 2

ER -