Improved assessment of coronary artery luminal stenosis with heavy calcifications using high-resolution photon-counting detector CT

Emily Koons, Patrick D. Vanmeter, Kishore Rajendran, Lifeng Yu, Cynthia McCollough, Shuai Leng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Coronary CT Angiography (cCTA) is commonly used to detect and quantify luminal stenoses in patients with coronary artery disease (CAD). However, its use is limited in patients with heavy coronary calcifications due to calcium blooming, which is caused by insufficient spatial resolution. This study evaluated the ability of a photon-counting-detector (PCD) CT in quantifying of luminal stenosis in the presence of heavy calcifications relative to an energy-integrating-detector (EID) CT. The phantom results indicate that with PCD-CT, luminal stenoses that were previously considered non-assessable due to the presence of heavily-calcified plaques can be assessed using cCTA.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2022
Subtitle of host publicationPhysics of Medical Imaging
EditorsWei Zhao, Lifeng Yu
PublisherSPIE
ISBN (Electronic)9781510649378
DOIs
StatePublished - 2022
EventMedical Imaging 2022: Physics of Medical Imaging - Virtual, Online
Duration: Mar 21 2022Mar 27 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12031
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2022: Physics of Medical Imaging
CityVirtual, Online
Period3/21/223/27/22

Keywords

  • Calcifications
  • Coronary Artery Disease (CAD)
  • Coronary CT Angiography (cCTA)
  • Photon Counting Detector CT (PCDCT)
  • Stenosis

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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