Impedance-pH Testing

Nicolas Villa; Marcelo F. Vela

doi:10.1016/j.gtc.2012.11.003

Impedance-pH Testing

Nicolas Villa, Marcelo F. Vela

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Pharmacologic treatment of gastroesophageal reflux disease is based upon gastric acid suppression with proton pump inhibitors (PPIs). In many patients, symptoms persist despite PPI treatment. For some, ongoing symptoms may be due to nonacid reflux. Accurate measurement of nonacid reflux is not possible with conventional ambulatory pH monitoring. Impedance-pH monitoring has advanced the ability to assess gastroesophageal reflux, because, in addition to detecting acid reflux, it enables measurement of nonacid reflux. This article discusses the principles of impedance-pH monitoring, catheter characteristics and placement, interpretation of studies, and clinical uses of this form of reflux monitoring.

Original language	English (US)
Pages (from-to)	17-26
Number of pages	10
Journal	Gastroenterology Clinics of North America
Volume	42
Issue number	1
DOIs	https://doi.org/10.1016/j.gtc.2012.11.003
State	Published - Mar 2013

Keywords

Gastroesophageal reflux
Impedance-pH
Nonacid reflux

ASJC Scopus subject areas

Gastroenterology

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10.1016/j.gtc.2012.11.003

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AB - Pharmacologic treatment of gastroesophageal reflux disease is based upon gastric acid suppression with proton pump inhibitors (PPIs). In many patients, symptoms persist despite PPI treatment. For some, ongoing symptoms may be due to nonacid reflux. Accurate measurement of nonacid reflux is not possible with conventional ambulatory pH monitoring. Impedance-pH monitoring has advanced the ability to assess gastroesophageal reflux, because, in addition to detecting acid reflux, it enables measurement of nonacid reflux. This article discusses the principles of impedance-pH monitoring, catheter characteristics and placement, interpretation of studies, and clinical uses of this form of reflux monitoring.

KW - Gastroesophageal reflux

KW - Impedance-pH

KW - Nonacid reflux

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Impedance-pH Testing

Abstract

Keywords

ASJC Scopus subject areas

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