Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess

James S. Molton, Yen Lin Chee, Tiffany P. Hennedige, Sudhakar K. Venkatesh, Sophia Archuleta

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis.

Original languageEnglish (US)
Article numbere0140129
JournalPloS one
Volume10
Issue number10
DOIs
StatePublished - Oct 7 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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