Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess

James S. Molton, Yen Lin Chee, Tiffany P. Hennedige, Sudhakar K Venkatesh, Sophia Archuleta

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis.

Original languageEnglish (US)
Article numbere0140129
JournalPLoS One
Volume10
Issue number10
DOIs
StatePublished - Oct 7 2015

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thrombophlebitis
liver abscess
Liver Abscess
Thrombophlebitis
Klebsiella pneumoniae
thrombosis
Liver
Veins
Thrombosis
Klebsiella
Hepatic Veins
emerging diseases
abscess
Portal Vein
Natural History
natural history
retrospective studies
Abscess
Retrospective Studies
therapeutics

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess. / Molton, James S.; Chee, Yen Lin; Hennedige, Tiffany P.; Venkatesh, Sudhakar K; Archuleta, Sophia.

In: PLoS One, Vol. 10, No. 10, e0140129, 07.10.2015.

Research output: Contribution to journalArticle

Molton, James S. ; Chee, Yen Lin ; Hennedige, Tiffany P. ; Venkatesh, Sudhakar K ; Archuleta, Sophia. / Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess. In: PLoS One. 2015 ; Vol. 10, No. 10.
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