Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Tumpa Dutta, Yogish C Kudva, Xuan Mai T Persson, Louis A. Schenck, G. Charles Ford, Ravinder Jit Singh, Rickey E. Carter, K Sreekumaran Nair

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Context: Poor glycemic control in individuals with type 1 diabetes (T1D) is associated with both micro-and macrovascular complications, but good glycemic control does not fully prevent the risk of these complications. Objective: The objective of the study was to determine whether T1D with good glycemic control have persistent abnormalities of metabolites and pathways that exist in T1D with poor glycemic control. Design:Wecompared plasma metabolites in T1D with poor (glycated hemoglobin≥8.5%, T1D[≥] and good (glycated hemoglobin

Original languageEnglish (US)
Pages (from-to)1023-1033
Number of pages11
JournalJournal of Clinical Endocrinology and Metabolism
Volume101
Issue number4
DOIs
StatePublished - Mar 1 2016

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Endocrinology
  • Biochemistry, medical
  • Endocrinology, Diabetes and Metabolism

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