Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Tumpa Dutta; Yogish C Kudva; Xuan Mai T Persson; Louis A. Schenck; G. Charles Ford; Ravinder Jit Singh; Rickey E. Carter; K Sreekumaran Nair

doi:10.1210/jc.2015-2640

Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Tumpa Dutta, Yogish C Kudva, Xuan Mai T Persson, Louis A. Schenck, G. Charles Ford, Ravinder Jit Singh, Rickey E. Carter, K Sreekumaran Nair

Research output: Contribution to journal › Article

19 Scopus citations

Abstract

Context: Poor glycemic control in individuals with type 1 diabetes (T1D) is associated with both micro-and macrovascular complications, but good glycemic control does not fully prevent the risk of these complications. Objective: The objective of the study was to determine whether T1D with good glycemic control have persistent abnormalities of metabolites and pathways that exist in T1D with poor glycemic control. Design:Wecompared plasma metabolites in T1D with poor (glycated hemoglobin≥8.5%, T1D[≥] and good (glycated hemoglobin

Original language	English (US)
Pages (from-to)	1023-1033
Number of pages	11
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	101
Issue number	4
DOIs	https://doi.org/10.1210/jc.2015-2640
State	Published - Mar 1 2016

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Endocrinology
Biochemistry, medical
Endocrinology, Diabetes and Metabolism

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Dutta, T., Kudva, Y. C., Persson, X. M. T., Schenck, L. A., Charles Ford, G., Singh, R. J., Carter, R. E., & Nair, K. S. (2016). Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people. Journal of Clinical Endocrinology and Metabolism, 101(4), 1023-1033. https://doi.org/10.1210/jc.2015-2640

Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people. / Dutta, Tumpa; Kudva, Yogish C; Persson, Xuan Mai T; Schenck, Louis A.; Charles Ford, G.; Singh, Ravinder Jit ; Carter, Rickey E.; Nair, K Sreekumaran.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 101, No. 4, 01.03.2016, p. 1023-1033.

Research output: Contribution to journal › Article

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