Impact of Gender and Age on In Vivo Virtual Histology-Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry)

Jie Qian, Akiko Maehara, Gary S. Mintz, M. Pauliina Margolis, Amir Lerman, Jason Rogers, Shuel Banai, Samer Kazziha, Celia Castellanos, Lokesh Dani, Martin Fahy, Gregg W. Stone, Martin B. Leon

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (<58, 58 to 68, and >68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).

Original languageEnglish (US)
Pages (from-to)1210-1214
Number of pages5
JournalAmerican Journal of Cardiology
Volume103
Issue number9
DOIs
StatePublished - May 1 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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