Impact of BMI on ability to successfully create an IPAA

Mohammad A. Khasawneh, Nicholas P. Mckenna, Zaid M. Abdelsattar, Angela Johnson, Eric Dozois, John H. Pemberton, Kellie L. Mathis

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

BACKGROUND: IPAA is the surgical treatment of choice for patients with ulcerative colitis. Limited data exist on how obesity impacts the ability of the surgeon to successfully create an IPAA. OBJECTIVE: We aimed to determine how BMI affects the ability to successfully complete the operation. DESIGN: This was a retrospective cohort study. SETTINGS: The study was conducted at a single tertiary care center. PATIENTS: We included all of the patients undergoing an IPAA for ulcerative colitis between January 2002 and August 2013 at our institution. A total of 1175 patients underwent proctocolectomy for ulcerative colitis during the study period; 129 were not offered IPAA (reasons included patient preference (n = 53), advanced age/comorbidity (n = 28), obesity (n = 23), incontinence (n = 8), suspicion of Crohn's disease (n = 8), rectal cancer (n = 3), and other (n = 6)). Twenty-six patients had a concurrent cancer diagnosis, and 5 had a polyposis syndrome. MAIN OUTCOME MEASURES: We used logistic regression modeling to estimate the association between BMI and unsuccessful pouch attempts. RESULTS: Of the 1046 patients offered IPAA, 19 (1.82%) could not be technically completed at the time of surgery. Increasing BMI was associated with a higher risk of not being able to technically perform IPAA (OR = 1.26 (95% CI, 1.17-1.34)). The chance of an unsuccessful pouch rose from 2.0% at a BMI of 30 to 5.7% at a BMI of 35 and 15.0% at a BMI of 40 (p < 0.01). The area under the receiver operator characteristics curve was 0.82. BMI explained 21% of the variation in pouch success rate. LIMITATIONS: This study is limited in its generalizability. Also, the verbosity within the operative dictations varied among surgeons, making it impossible to be certain which maneuvers were performed to gain length in each patient. In addition, we were limited to BMI as a surrogate for visceral obesity, and we did not include medical therapy at the time of IPAA attempt. CONCLUSIONS: There is a strong association between increasing BMI and the ability to technically perform IPAA. Obese patients should be counseled to lose weight preoperatively to increase the probability of successful IPAA construction at the time of operation.

Original languageEnglish (US)
Pages (from-to)1034-1038
Number of pages5
JournalDiseases of the Colon and Rectum
Volume59
Issue number11
DOIs
StatePublished - Nov 1 2016

Fingerprint

Ulcerative Colitis
Obesity
Abdominal Obesity
Patient Preference
Rectal Neoplasms
Tertiary Care Centers
Crohn Disease
Comorbidity
Cohort Studies
Retrospective Studies
Logistic Models
Weights and Measures
Therapeutics
Neoplasms
Surgeons

Keywords

  • BMI
  • IPAA
  • Obesity
  • Outcomes
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Khasawneh, M. A., Mckenna, N. P., Abdelsattar, Z. M., Johnson, A., Dozois, E., Pemberton, J. H., & Mathis, K. L. (2016). Impact of BMI on ability to successfully create an IPAA. Diseases of the Colon and Rectum, 59(11), 1034-1038. https://doi.org/10.1097/DCR.0000000000000686

Impact of BMI on ability to successfully create an IPAA. / Khasawneh, Mohammad A.; Mckenna, Nicholas P.; Abdelsattar, Zaid M.; Johnson, Angela; Dozois, Eric; Pemberton, John H.; Mathis, Kellie L.

In: Diseases of the Colon and Rectum, Vol. 59, No. 11, 01.11.2016, p. 1034-1038.

Research output: Contribution to journalArticle

Khasawneh, MA, Mckenna, NP, Abdelsattar, ZM, Johnson, A, Dozois, E, Pemberton, JH & Mathis, KL 2016, 'Impact of BMI on ability to successfully create an IPAA', Diseases of the Colon and Rectum, vol. 59, no. 11, pp. 1034-1038. https://doi.org/10.1097/DCR.0000000000000686
Khasawneh MA, Mckenna NP, Abdelsattar ZM, Johnson A, Dozois E, Pemberton JH et al. Impact of BMI on ability to successfully create an IPAA. Diseases of the Colon and Rectum. 2016 Nov 1;59(11):1034-1038. https://doi.org/10.1097/DCR.0000000000000686
Khasawneh, Mohammad A. ; Mckenna, Nicholas P. ; Abdelsattar, Zaid M. ; Johnson, Angela ; Dozois, Eric ; Pemberton, John H. ; Mathis, Kellie L. / Impact of BMI on ability to successfully create an IPAA. In: Diseases of the Colon and Rectum. 2016 ; Vol. 59, No. 11. pp. 1034-1038.
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