Impact of a Multidisciplinary Tumor Board on the Care of Patients with Histiocytic Disorders: The Histiocytosis Working Group experience

Gaurav Goyal, Jason R. Young, Jithma P. Abeykoon, Mithun V. Shah, N. Nora Bennani, Julio C. Sartori-Valinotti, Robert Vassallo, Jay H. Ryu, W. Oliver Tobin, Matthew J. Koster, Caroline J. Davidge-Pitts, Aishwarya Ravindran, Karen L. Rech, Ronald S. Go

Research output: Contribution to journalArticlepeer-review

Abstract

INTRODUCTION: Histiocytic disorders pose significant diagnostic and management challenges for the clinicians due to diverse clinical manifestations and often non-specific histopathologic findings. Herein, we report the tumor board experience from the first-of-its-kind Histiocytosis Working Group (HWG). MATERIALS AND METHODS: The HWG was established in June 2017 and consists of experts from 10 subspecialties that discuss cases in a multidisciplinary format. We present the outcome of tumor board case discussions during the first 2 years since its inception (June 2017-June 2019). RESULTS: Forty cases with a suspected histiocytic disorder were reviewed at HWG during this time period. Average number of subspecialties involved in HWG case discussion was 5 (range, 2-9). Histiocytosis Working Group tumor board recommendations led to significant changes in the care of 24 (60%) patients. These included change in diagnosis (n = 11, 27%) and change in treatment (n = 13, 33%). CONCLUSION: Our report highlights the feasibility of a multidisciplinary tumor board and its impact on outcomes of patients with histiocytic disorders.

Original languageEnglish (US)
Pages (from-to)144-148
Number of pages5
JournalThe oncologist
Volume27
Issue number2
DOIs
StatePublished - Mar 4 2022

Keywords

  • Erdheim–Chester disease
  • giant cell tumor of tendon sheath
  • histiocytes
  • immunoglobulin G4-related disease
  • osteopoikilosis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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