Immunosuppression by anti-cd4 treatment in vivo

M. Weyand Cornelia; Goronzy Jorg; Swarztrauber Kari; C. Garrison Fathman

doi:10.1097/00007890-198906000-00023

Immunosuppression by anti-cd4 treatment in vivo

M. Weyand Cornelia, Goronzy Jorg, Swarztrauber Kari, C. Garrison Fathman

Immunology

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Elimination of CD4+ helper T cells by treatment with monoclonal antibodies (mcAb) in vivo has been used as a new mode of immunosuppression in organ transplantation and autoimmune diseases. To explore the potential risks of this therapeutic approach we have studied antiviral responses in mice depleted of CD4+ T cells.

Original language	English (US)
Pages (from-to)	1034-1038
Number of pages	5
Journal	Transplantation
Volume	47
Issue number	6
DOIs	https://doi.org/10.1097/00007890-198906000-00023
State	Published - Jun 1989

ASJC Scopus subject areas

Transplantation

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title = "Immunosuppression by anti-cd4 treatment in vivo",

abstract = "Elimination of CD4+ helper T cells by treatment with monoclonal antibodies (mcAb) in vivo has been used as a new mode of immunosuppression in organ transplantation and autoimmune diseases. To explore the potential risks of this therapeutic approach we have studied antiviral responses in mice depleted of CD4+ T cells.",

author = "Cornelia, {M. Weyand} and Goronzy Jorg and Swarztrauber Kari and Fathman, {C. Garrison}",

year = "1989",

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AB - Elimination of CD4+ helper T cells by treatment with monoclonal antibodies (mcAb) in vivo has been used as a new mode of immunosuppression in organ transplantation and autoimmune diseases. To explore the potential risks of this therapeutic approach we have studied antiviral responses in mice depleted of CD4+ T cells.

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Immunosuppression by anti-cd4 treatment in vivo

Abstract

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