Immunosuppression by anti-cd4 treatment in vivo

M. Weyand Cornelia, Goronzy Jorg, Swarztrauber Kari, C. Garrison Fathman

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Elimination of CD4+ helper T cells by treatment with monoclonal antibodies (mcAb) in vivo has been used as a new mode of immunosuppression in organ transplantation and autoimmune diseases. To explore the potential risks of this therapeutic approach we have studied antiviral responses in mice depleted of CD4+ T cells.

Original languageEnglish (US)
Pages (from-to)1034-1038
Number of pages5
JournalTransplantation
Volume47
Issue number6
DOIs
StatePublished - Jun 1989

ASJC Scopus subject areas

  • Transplantation

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