Immunology of the Liver and Mechanisms of Inflammation

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A decade ago the liver was simply considered as the main organ for metabolism and de-toxification of endogenous and exogenous substances. During the past ten years studies indicate that the liver also plays a key role in several immunological events some of which contribute to development of autoimmune hepatic disease (i.e., primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis), liver inflammation and fibrosis. Therefore, better elucidation of the immunology of the liver will improve the understanding of hepatic diseases.

Original languageEnglish (US)
Title of host publicationPractical Gastroenterology and Hepatology: Liver and Biliary Disease
PublisherWiley-Blackwell
Pages17-22
Number of pages6
ISBN (Print)9781405182751
DOIs
StatePublished - Aug 31 2010

Fingerprint

Allergy and Immunology
Inflammation
Liver
Autoimmune Hepatitis
Sclerosing Cholangitis
Biliary Liver Cirrhosis
Liver Cirrhosis
Autoimmune Diseases

Keywords

  • Adaptive immunity
  • Fibrosis
  • Inflammation
  • Innate immunity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lazaridis, K. N. (2010). Immunology of the Liver and Mechanisms of Inflammation. In Practical Gastroenterology and Hepatology: Liver and Biliary Disease (pp. 17-22). Wiley-Blackwell. https://doi.org/10.1002/9781444325249.ch2

Immunology of the Liver and Mechanisms of Inflammation. / Lazaridis, Konstantinos N.

Practical Gastroenterology and Hepatology: Liver and Biliary Disease. Wiley-Blackwell, 2010. p. 17-22.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lazaridis, KN 2010, Immunology of the Liver and Mechanisms of Inflammation. in Practical Gastroenterology and Hepatology: Liver and Biliary Disease. Wiley-Blackwell, pp. 17-22. https://doi.org/10.1002/9781444325249.ch2
Lazaridis KN. Immunology of the Liver and Mechanisms of Inflammation. In Practical Gastroenterology and Hepatology: Liver and Biliary Disease. Wiley-Blackwell. 2010. p. 17-22 https://doi.org/10.1002/9781444325249.ch2
Lazaridis, Konstantinos N. / Immunology of the Liver and Mechanisms of Inflammation. Practical Gastroenterology and Hepatology: Liver and Biliary Disease. Wiley-Blackwell, 2010. pp. 17-22
@inbook{aa0641a44fe44fb681bc122385d45279,
title = "Immunology of the Liver and Mechanisms of Inflammation",
abstract = "A decade ago the liver was simply considered as the main organ for metabolism and de-toxification of endogenous and exogenous substances. During the past ten years studies indicate that the liver also plays a key role in several immunological events some of which contribute to development of autoimmune hepatic disease (i.e., primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis), liver inflammation and fibrosis. Therefore, better elucidation of the immunology of the liver will improve the understanding of hepatic diseases.",
keywords = "Adaptive immunity, Fibrosis, Inflammation, Innate immunity",
author = "Lazaridis, {Konstantinos N}",
year = "2010",
month = "8",
day = "31",
doi = "10.1002/9781444325249.ch2",
language = "English (US)",
isbn = "9781405182751",
pages = "17--22",
booktitle = "Practical Gastroenterology and Hepatology: Liver and Biliary Disease",
publisher = "Wiley-Blackwell",

}

TY - CHAP

T1 - Immunology of the Liver and Mechanisms of Inflammation

AU - Lazaridis, Konstantinos N

PY - 2010/8/31

Y1 - 2010/8/31

N2 - A decade ago the liver was simply considered as the main organ for metabolism and de-toxification of endogenous and exogenous substances. During the past ten years studies indicate that the liver also plays a key role in several immunological events some of which contribute to development of autoimmune hepatic disease (i.e., primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis), liver inflammation and fibrosis. Therefore, better elucidation of the immunology of the liver will improve the understanding of hepatic diseases.

AB - A decade ago the liver was simply considered as the main organ for metabolism and de-toxification of endogenous and exogenous substances. During the past ten years studies indicate that the liver also plays a key role in several immunological events some of which contribute to development of autoimmune hepatic disease (i.e., primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis), liver inflammation and fibrosis. Therefore, better elucidation of the immunology of the liver will improve the understanding of hepatic diseases.

KW - Adaptive immunity

KW - Fibrosis

KW - Inflammation

KW - Innate immunity

UR - http://www.scopus.com/inward/record.url?scp=84886012613&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886012613&partnerID=8YFLogxK

U2 - 10.1002/9781444325249.ch2

DO - 10.1002/9781444325249.ch2

M3 - Chapter

AN - SCOPUS:84886012613

SN - 9781405182751

SP - 17

EP - 22

BT - Practical Gastroenterology and Hepatology: Liver and Biliary Disease

PB - Wiley-Blackwell

ER -