Immunology of the Liver and Mechanisms of Inflammation

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A decade ago the liver was simply considered as the main organ for metabolism and de-toxification of endogenous and exogenous substances. During the past ten years studies indicate that the liver also plays a key role in several immunological events some of which contribute to development of autoimmune hepatic disease (i.e., primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis), liver inflammation and fibrosis. Therefore, better elucidation of the immunology of the liver will improve the understanding of hepatic diseases.

Original languageEnglish (US)
Title of host publicationPractical Gastroenterology and Hepatology
Subtitle of host publicationLiver and Biliary Disease
PublisherWiley-Blackwell
Pages17-22
Number of pages6
ISBN (Print)9781405182751
DOIs
StatePublished - Aug 31 2010

Keywords

  • Adaptive immunity
  • Fibrosis
  • Inflammation
  • Innate immunity

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Lazaridis, K. N. (2010). Immunology of the Liver and Mechanisms of Inflammation. In Practical Gastroenterology and Hepatology: Liver and Biliary Disease (pp. 17-22). Wiley-Blackwell. https://doi.org/10.1002/9781444325249.ch2