Imaging of remyelination and neuronal health

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

Remyelination of axons that have been demyelinated due to multiple sclerosis (MS) may be a critical step in restoring the damaged axons and reversing the disease process. While it is possible to establish the presence of remyelination with microscopy of tissue samples, it is important to have noninvasive or minimally invasive methods to measure remyelination in living animals and humans. Such tools are critical to establishing the efficacy of agents purported to promote or enhance remyelination. This chapter reviews the technology of imaging of the brain, its application to MS, and the current state of imaging techniques for measuring remyelination and the health of the associated neurons in the setting of MS.

Original languageEnglish (US)
Title of host publicationAdvances in multiple Sclerosis and Experimental Demyelinating Diseases
EditorsMoses Rodriguez
Pages73-92
Number of pages20
DOIs
StatePublished - Dec 1 2008

Publication series

NameCurrent Topics in Microbiology and Immunology
Volume318
ISSN (Print)0070-217X

ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)

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    Erickson, B. J. (2008). Imaging of remyelination and neuronal health. In M. Rodriguez (Ed.), Advances in multiple Sclerosis and Experimental Demyelinating Diseases (pp. 73-92). (Current Topics in Microbiology and Immunology; Vol. 318). https://doi.org/10.1007/978-3-540-73677-6-4