Imaging of malignancies of the biliary tract- an update

Tiffany Priyanthi Hennedige, Wee Thong Neo, Sudhakar K Venkatesh

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Malignancies of the biliary tract include cholangiocarcinoma, gallbladder cancers and carcinoma of the ampulla of Vater. Biliary tract adenocarcinomas are the second most common primary hepatobiliary cancer. Due to their slow growing nature, non-specific and late symptomatology, these malignancies are often diagnosed in advanced stages with poor prognosis. Apart from incidental discovery of gall bladder carcinoma upon cholecystectomy, early stage biliary tract cancers are now detected with computed tomography (CT) and magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP). Accurate characterization and staging of these indolent cancers will determine outcome as majority of the patients' are inoperable at the time of presentation. Ultrasound is useful for initial evaluation of the biliary tract and gallbladder masses and in determining the next suitable modality for further evaluation. Multimodality imaging plays an integral role in the management of the biliary tract malignancies. The imaging techniques most useful are MRI with MRCP, endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound (EUS) and positron emission tomography (PET). In this review we will discuss epidemiology and the role of imaging in detection, characterization and management of the biliary tract malignancies under the three broad categories of cholangiocarcinomas (intra- and extrahepatic), gallbladder cancers and ampullary carcinomas.

Original languageEnglish (US)
Article number14
JournalCancer Imaging
Volume14
Issue number1
DOIs
StatePublished - Apr 22 2014

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Biliary Tract
Cholangiocarcinoma
Magnetic Resonance Cholangiopancreatography
Gallbladder Neoplasms
Neoplasms
Carcinoma
Magnetic Resonance Imaging
Biliary Tract Neoplasms
Ampulla of Vater
Incidental Findings
Neoplasm Staging
Endoscopic Retrograde Cholangiopancreatography
Cholecystectomy
Gallbladder
Positron-Emission Tomography
Epidemiology
Urinary Bladder
Adenocarcinoma
Tomography

Keywords

  • Ampullary carcinoma
  • Biliary tract
  • Cholangiocarcinoma
  • CT
  • Gall bladder carcinoma
  • Malignancies
  • MRI
  • Ultrasound

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Imaging of malignancies of the biliary tract- an update. / Hennedige, Tiffany Priyanthi; Neo, Wee Thong; Venkatesh, Sudhakar K.

In: Cancer Imaging, Vol. 14, No. 1, 14, 22.04.2014.

Research output: Contribution to journalArticle

Hennedige, Tiffany Priyanthi ; Neo, Wee Thong ; Venkatesh, Sudhakar K. / Imaging of malignancies of the biliary tract- an update. In: Cancer Imaging. 2014 ; Vol. 14, No. 1.
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