TY - JOUR
T1 - Imaging of Hepatic Fibrosis
AU - Mathew, Rishi Philip
AU - Venkatesh, Sudhakar Kundapur
N1 - Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Purpose of Review: The purpose of this review is to discuss the current imaging techniques for non-invasive assessment of liver fibrosis (LF). Recent Findings: Elastography-based techniques are the most widely used imaging methods for the evaluation of LF. Currently, MR elastography (MRE) is the most accurate non-invasive method for detection and staging of LF. Ultrasound-based vibration-controlled transient elastography (VCTE) is the most widely used as it can be easily performed at the point of care but has technical limitations especially in the obese. Innovations and technical improvements continue to evolve in elastography for improving accuracy and avoiding misinterpretation from confounding factors. Other imaging methods including diffusion-weighted imaging (DWI), hepatocellular contrast-enhanced (HCE) MRI, T1 relaxometry, T1ρ imaging, textural analysis, liver surface nodularity, susceptibility-weighted imaging, and perfusion imaging are promising but need further evaluation and clinical validation. Summary: MRE is the most accurate imaging technique for assessment of LF.
AB - Purpose of Review: The purpose of this review is to discuss the current imaging techniques for non-invasive assessment of liver fibrosis (LF). Recent Findings: Elastography-based techniques are the most widely used imaging methods for the evaluation of LF. Currently, MR elastography (MRE) is the most accurate non-invasive method for detection and staging of LF. Ultrasound-based vibration-controlled transient elastography (VCTE) is the most widely used as it can be easily performed at the point of care but has technical limitations especially in the obese. Innovations and technical improvements continue to evolve in elastography for improving accuracy and avoiding misinterpretation from confounding factors. Other imaging methods including diffusion-weighted imaging (DWI), hepatocellular contrast-enhanced (HCE) MRI, T1 relaxometry, T1ρ imaging, textural analysis, liver surface nodularity, susceptibility-weighted imaging, and perfusion imaging are promising but need further evaluation and clinical validation. Summary: MRE is the most accurate imaging technique for assessment of LF.
KW - Functional imaging
KW - Liver fibrosis
KW - Magnetic resonance elastography
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U2 - 10.1007/s11894-018-0652-7
DO - 10.1007/s11894-018-0652-7
M3 - Review article
C2 - 30159792
AN - SCOPUS:85052576173
SN - 1522-8037
VL - 20
JO - Current gastroenterology reports
JF - Current gastroenterology reports
IS - 10
M1 - 45
ER -