Imaging features of toxicities associated with immune checkpoint inhibitors

Babina Gosangi; Lacey McIntosh; Abhishek Keraliya; David Victor Kumar Irugu; Akshay Baheti; Ashish Khandelwal; Richard Thomas; Marta Braschi-Amirfarzan

doi:10.1016/j.ejro.2022.100434

Imaging features of toxicities associated with immune checkpoint inhibitors

Babina Gosangi, Lacey McIntosh, Abhishek Keraliya, David Victor Kumar Irugu, Akshay Baheti, Ashish Khandelwal, Richard Thomas, Marta Braschi-Amirfarzan

Radiology

Research output: Contribution to journal › Article › peer-review

Abstract

The past decade has witnessed a change in landscape of cancer management with the advent of precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and have played an important role in improving patient survival. While the patients are living longer, treatment with ICIs are sometimes associated with adverse effects, some of which could be fatal. Radiologists can play a crucial role by early identification of some of these adverse effects during restaging scans. Our paper focuses on the imaging features of commonly occurring ICI toxicities based on organ system.

Original language	English (US)
Article number	100434
Journal	European Journal of Radiology Open
Volume	9
DOIs	https://doi.org/10.1016/j.ejro.2022.100434
State	Published - Jan 2022

Keywords

Colitis
Hepatitis
Immune check point inhibitors toxicity
Pancreatitis
Pneumonitis

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.ejro.2022.100434

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title = "Imaging features of toxicities associated with immune checkpoint inhibitors",

abstract = "The past decade has witnessed a change in landscape of cancer management with the advent of precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and have played an important role in improving patient survival. While the patients are living longer, treatment with ICIs are sometimes associated with adverse effects, some of which could be fatal. Radiologists can play a crucial role by early identification of some of these adverse effects during restaging scans. Our paper focuses on the imaging features of commonly occurring ICI toxicities based on organ system.",

keywords = "Colitis, Hepatitis, Immune check point inhibitors toxicity, Pancreatitis, Pneumonitis",

author = "Babina Gosangi and Lacey McIntosh and Abhishek Keraliya and Irugu, {David Victor Kumar} and Akshay Baheti and Ashish Khandelwal and Richard Thomas and Marta Braschi-Amirfarzan",

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doi = "10.1016/j.ejro.2022.100434",

language = "English (US)",

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AU - Gosangi, Babina

AU - McIntosh, Lacey

AU - Keraliya, Abhishek

AU - Irugu, David Victor Kumar

AU - Baheti, Akshay

AU - Khandelwal, Ashish

AU - Thomas, Richard

AU - Braschi-Amirfarzan, Marta

PY - 2022/1

Y1 - 2022/1

N2 - The past decade has witnessed a change in landscape of cancer management with the advent of precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and have played an important role in improving patient survival. While the patients are living longer, treatment with ICIs are sometimes associated with adverse effects, some of which could be fatal. Radiologists can play a crucial role by early identification of some of these adverse effects during restaging scans. Our paper focuses on the imaging features of commonly occurring ICI toxicities based on organ system.

AB - The past decade has witnessed a change in landscape of cancer management with the advent of precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and have played an important role in improving patient survival. While the patients are living longer, treatment with ICIs are sometimes associated with adverse effects, some of which could be fatal. Radiologists can play a crucial role by early identification of some of these adverse effects during restaging scans. Our paper focuses on the imaging features of commonly occurring ICI toxicities based on organ system.

KW - Colitis

KW - Hepatitis

KW - Immune check point inhibitors toxicity

KW - Pancreatitis

KW - Pneumonitis

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JO - European Journal of Radiology Open

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ER -

Imaging features of toxicities associated with immune checkpoint inhibitors

Abstract

Keywords

ASJC Scopus subject areas

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