Image-guided ablation of painful metastatic bone tumors

A new and effective approach to a difficult problem

Matthew R Callstrom, J. William Charboneau, Matthew Philip Goetz, Joseph Rubin, Thomas D. Atwell, Michael A. Farrell, Timothy J. Welch, Timothy Maus

Research output: Contribution to journalArticle

142 Citations (Scopus)

Abstract

Painful skeletal metastases are a common problem in cancer patients. Although external beam radiation therapy is the current standard of care for cancer patients who present with localized bone pain, 20-30% of patients treated with this modality do not experience pain relief, and few further options exist for these patients. For many patients with painful metastatic skeletal disease, analgesics remain the only alternative treatment option. Recently, image-guided percutaneous methods of tumor destruction have proven effective for treatment of this difficult problem. This review describes the application, limitations, and effectiveness of percutaneous ablative methods including ethanol, methyl methacrylate, laser-induced interstitial thermotherapy (LITT), cryoablation, and percutaneous radiofrequency ablation (RFA) for palliation of painful skeletal metastases.

Original languageEnglish (US)
Pages (from-to)1-15
Number of pages15
JournalSkeletal Radiology
Volume35
Issue number1
DOIs
StatePublished - Jan 2006

Fingerprint

Bone and Bones
Neoplasms
Neoplasm Metastasis
Pain
Cryosurgery
Induced Hyperthermia
Methacrylates
Standard of Care
Analgesics
Lasers
Ethanol
Radiotherapy
Therapeutics

Keywords

  • Ablation
  • Bone
  • Metastases
  • Palliation
  • Percutaneous

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Image-guided ablation of painful metastatic bone tumors : A new and effective approach to a difficult problem. / Callstrom, Matthew R; Charboneau, J. William; Goetz, Matthew Philip; Rubin, Joseph; Atwell, Thomas D.; Farrell, Michael A.; Welch, Timothy J.; Maus, Timothy.

In: Skeletal Radiology, Vol. 35, No. 1, 01.2006, p. 1-15.

Research output: Contribution to journalArticle

Callstrom, Matthew R ; Charboneau, J. William ; Goetz, Matthew Philip ; Rubin, Joseph ; Atwell, Thomas D. ; Farrell, Michael A. ; Welch, Timothy J. ; Maus, Timothy. / Image-guided ablation of painful metastatic bone tumors : A new and effective approach to a difficult problem. In: Skeletal Radiology. 2006 ; Vol. 35, No. 1. pp. 1-15.
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