Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy

Cristian A. Linte, Jon J. Camp, Maryam E. Rettmann, David R. Holmes III, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

In spite of significant efforts to enhance guidance for catheter navigation, limited research has been conducted to consider the changes that occur in the tissue during ablation as means to provide useful feedback on the progression of therapy delivery. We propose a technique to visualize lesion progression and monitor the effects of the RF energy delivery using a surrogate thermal ablation model. The model incorporates both physical and physiological tissue parameters, and uses heat transfer principles to estimate temperature distribution in the tissue and geometry of the generated lesion in near real time. The ablation model has been calibrated and evaluated using ex vivo beef muscle tissue in a clinically relevant ablation protocol. To validate the model, the predicted temperature distribution was assessed against that measured directly using fiberoptic temperature probes inserted in the tissue. Moreover, the model-predicted lesions were compared to the lesions observed in the post-ablation digital images. Results showed an agreement within 5°C between the model-predicted and experimentally measured tissue temperatures, as well as comparable predicted and observed lesion characteristics and geometry. These results suggest that the proposed technique is capable of providing reasonably accurate and sufficiently fast representations of the created RF ablation lesions, to generate lesion maps in near real time. These maps can be used to guide the placement of successive lesions to ensure continuous and enduring suppression of the arrhythmic pathway.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Volume8671
DOIs
StatePublished - 2013
EventMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling - Lake Buena Vista, FL, United States
Duration: Feb 12 2013Feb 14 2013

Other

OtherMedical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CityLake Buena Vista, FL
Period2/12/132/14/13

Fingerprint

arrhythmia
Cardiac Arrhythmias
Ablation
lesions
ablation
Therapy
therapy
Tissue
Modeling
Temperature Distribution
Progression
Temperature distribution
progressions
Model
Beef
delivery
temperature distribution
Geometry
Catheters
temperature probes

Keywords

  • Data integration for the clinic/OR
  • Evaluation and validation
  • Image-guided cardiac ablation
  • Image-guided cardiac procedures
  • Intra-operative modeling and monitoring
  • Intra-procedure visualization

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Linte, C. A., Camp, J. J., Rettmann, M. E., Holmes III, D. R., & Robb, R. A. (2013). Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 8671). [86710E] https://doi.org/10.1117/12.2008529

Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy. / Linte, Cristian A.; Camp, Jon J.; Rettmann, Maryam E.; Holmes III, David R.; Robb, Richard A.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8671 2013. 86710E.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Linte, CA, Camp, JJ, Rettmann, ME, Holmes III, DR & Robb, RA 2013, Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 8671, 86710E, Medical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling, Lake Buena Vista, FL, United States, 2/12/13. https://doi.org/10.1117/12.2008529
Linte CA, Camp JJ, Rettmann ME, Holmes III DR, Robb RA. Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8671. 2013. 86710E https://doi.org/10.1117/12.2008529
Linte, Cristian A. ; Camp, Jon J. ; Rettmann, Maryam E. ; Holmes III, David R. ; Robb, Richard A. / Image-based modeling and characterization of RF ablation lesions in cardiac arrhythmia therapy. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8671 2013.
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