IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

Santiago Barrio; Umair Munawar; Yuan Xiao Zhu; Nicola Giesen; Chang Xin Shi; Matteo Da Viá; Ricardo Sanchez; Laura Bruins; Theresa Demler; Nicole Müller; Larissa Haertle; Andoni Garitano; Torsten Steinbrunn; Sophia Danhof; Isabel Cuenca; Clara Barrio-Garcia; Esteban Braggio; Andreas Rosenwald; Joaquin Martinez-Lopez; Leo Rasche; Marc S. Raab; A. Keith Stewart; Hermann Einsele; Thorsten Stühmer; K. Martin Kortüm

doi:10.3324/HAEMATOL.2019.217943

IKZF1/3 and CRL4^CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

Santiago Barrio, Umair Munawar, Yuan Xiao Zhu, Nicola Giesen, Chang Xin Shi, Matteo Da Viá, Ricardo Sanchez, Laura Bruins, Theresa Demler, Nicole Müller, Larissa Haertle, Andoni Garitano, Torsten Steinbrunn, Sophia Danhof, Isabel Cuenca, Clara Barrio-Garcia, Esteban Braggio, Andreas Rosenwald, Joaquin Martinez-Lopez, Leo RascheMarc S. Raab, A. Keith Stewart, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm

Research output: Contribution to journal › Letter › peer-review

5 Scopus citations

Original language	English (US)
Pages (from-to)	E237-E241
Journal	Haematologica
Volume	105
Issue number	5
DOIs	https://doi.org/10.3324/HAEMATOL.2019.217943
State	Published - May 1 2020

ASJC Scopus subject areas

Hematology

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Barrio, S., Munawar, U., Zhu, Y. X., Giesen, N., Shi, C. X., Da Viá, M., Sanchez, R., Bruins, L., Demler, T., Müller, N., Haertle, L., Garitano, A., Steinbrunn, T., Danhof, S., Cuenca, I., Barrio-Garcia, C., Braggio, E., Rosenwald, A., Martinez-Lopez, J., ... Kortüm, K. M. (2020). IKZF1/3 and CRL4^CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma. Haematologica, 105(5), E237-E241. https://doi.org/10.3324/HAEMATOL.2019.217943

Barrio, S, Munawar, U, Zhu, YX, Giesen, N, Shi, CX, Da Viá, M, Sanchez, R, Bruins, L, Demler, T, Müller, N, Haertle, L, Garitano, A, Steinbrunn, T, Danhof, S, Cuenca, I, Barrio-Garcia, C, Braggio, E, Rosenwald, A, Martinez-Lopez, J, Rasche, L, Raab, MS, Stewart, AK, Einsele, H, Stühmer, T & Kortüm, KM 2020, 'IKZF1/3 and CRL4^CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma', Haematologica, vol. 105, no. 5, pp. E237-E241. https://doi.org/10.3324/HAEMATOL.2019.217943

@article{2b49c5e8c350459383e05ecf93b2ee93,

title = "IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma",

author = "Santiago Barrio and Umair Munawar and Zhu, {Yuan Xiao} and Nicola Giesen and Shi, {Chang Xin} and {Da Vi{\'a}}, Matteo and Ricardo Sanchez and Laura Bruins and Theresa Demler and Nicole M{\"u}ller and Larissa Haertle and Andoni Garitano and Torsten Steinbrunn and Sophia Danhof and Isabel Cuenca and Clara Barrio-Garcia and Esteban Braggio and Andreas Rosenwald and Joaquin Martinez-Lopez and Leo Rasche and Raab, {Marc S.} and Stewart, {A. Keith} and Hermann Einsele and Thorsten St{\"u}hmer and Kort{\"u}m, {K. Martin}",

note = "Funding Information: this work was supported by the Deutsche Forschungsgemeinschaft (KFO216), the IZKF, the BTHA and the CDW Stiftung (KMK). UM was supported by a grant of the German Excellence Initiative to the Graduate School of Life Sciences, University of W{\"u}rzburg.",

year = "2020",

month = may,

day = "1",

doi = "10.3324/HAEMATOL.2019.217943",

language = "English (US)",

volume = "105",

pages = "E237--E241",

journal = "Haematologica",

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publisher = "Ferrata Storti Foundation",

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TY - JOUR

T1 - IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

AU - Barrio, Santiago

AU - Munawar, Umair

AU - Zhu, Yuan Xiao

AU - Giesen, Nicola

AU - Shi, Chang Xin

AU - Da Viá, Matteo

AU - Sanchez, Ricardo

AU - Bruins, Laura

AU - Demler, Theresa

AU - Müller, Nicole

AU - Haertle, Larissa

AU - Garitano, Andoni

AU - Steinbrunn, Torsten

AU - Danhof, Sophia

AU - Cuenca, Isabel

AU - Barrio-Garcia, Clara

AU - Braggio, Esteban

AU - Rosenwald, Andreas

AU - Martinez-Lopez, Joaquin

AU - Rasche, Leo

AU - Raab, Marc S.

AU - Stewart, A. Keith

AU - Einsele, Hermann

AU - Stühmer, Thorsten

AU - Kortüm, K. Martin

N1 - Funding Information: this work was supported by the Deutsche Forschungsgemeinschaft (KFO216), the IZKF, the BTHA and the CDW Stiftung (KMK). UM was supported by a grant of the German Excellence Initiative to the Graduate School of Life Sciences, University of Würzburg.

PY - 2020/5/1

Y1 - 2020/5/1

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UR - http://www.scopus.com/inward/citedby.url?scp=85086035029&partnerID=8YFLogxK

U2 - 10.3324/HAEMATOL.2019.217943

DO - 10.3324/HAEMATOL.2019.217943

M3 - Letter

C2 - 31558666

AN - SCOPUS:85086035029

SN - 0390-6078

VL - 105

SP - E237-E241

JO - Haematologica

JF - Haematologica

IS - 5

ER -

IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

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IKZF1/3 and CRL4^CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma