Idiopathic thrombocytopenic purpura associated with breast cancer: A case report and review of the current literature

Luis F. Porrata; Steven Alberts; Christopher Hook; Curtis A. Hanson

doi:10.1097/00000421-199908000-00019

Idiopathic thrombocytopenic purpura associated with breast cancer: A case report and review of the current literature

Luis F. Porrata, Steven Alberts, Christopher Hook, Curtis A. Hanson

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The association of solid tumors with idiopathic thrombocytopenic purpura (ITP) is rare. Before this study, there have been three case reports indicating an association between breast cancer and ITP. We present a 69- year-old man with metastatic breast cancer and progressive thrombocytopenia without any evidence of a leukoerythroblastic picture or etiologies for the thrombocytopenia. Serum platelet antibodies were identified. A bone marrow biopsy showed small foci of metastatic breast cancer, thrombocytopenia, and normal number of megakaryocytes. A subsequent trial of steroids resulted in a marked improvement of the patient's thrombocytopenia. This is the fourth case report indicating an association of breast cancer and ITP.

Original language	English (US)
Pages (from-to)	411-413
Number of pages	3
Journal	American Journal of Clinical Oncology: Cancer Clinical Trials
Volume	22
Issue number	4
DOIs	https://doi.org/10.1097/00000421-199908000-00019
State	Published - Aug 1 1999

Keywords

Breast cancer
Idiopathic thrombocytopenic purpura
Thrombocytopenia

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1097/00000421-199908000-00019

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abstract = "The association of solid tumors with idiopathic thrombocytopenic purpura (ITP) is rare. Before this study, there have been three case reports indicating an association between breast cancer and ITP. We present a 69- year-old man with metastatic breast cancer and progressive thrombocytopenia without any evidence of a leukoerythroblastic picture or etiologies for the thrombocytopenia. Serum platelet antibodies were identified. A bone marrow biopsy showed small foci of metastatic breast cancer, thrombocytopenia, and normal number of megakaryocytes. A subsequent trial of steroids resulted in a marked improvement of the patient's thrombocytopenia. This is the fourth case report indicating an association of breast cancer and ITP.",

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AB - The association of solid tumors with idiopathic thrombocytopenic purpura (ITP) is rare. Before this study, there have been three case reports indicating an association between breast cancer and ITP. We present a 69- year-old man with metastatic breast cancer and progressive thrombocytopenia without any evidence of a leukoerythroblastic picture or etiologies for the thrombocytopenia. Serum platelet antibodies were identified. A bone marrow biopsy showed small foci of metastatic breast cancer, thrombocytopenia, and normal number of megakaryocytes. A subsequent trial of steroids resulted in a marked improvement of the patient's thrombocytopenia. This is the fourth case report indicating an association of breast cancer and ITP.

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Idiopathic thrombocytopenic purpura associated with breast cancer: A case report and review of the current literature

Abstract

Keywords

ASJC Scopus subject areas

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