Idiopathic thrombocytopenic purpura associated with breast cancer: A case report and review of the current literature

Luis F. Porrata, Steven Alberts, Christopher Hook, Curtis A. Hanson

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The association of solid tumors with idiopathic thrombocytopenic purpura (ITP) is rare. Before this study, there have been three case reports indicating an association between breast cancer and ITP. We present a 69- year-old man with metastatic breast cancer and progressive thrombocytopenia without any evidence of a leukoerythroblastic picture or etiologies for the thrombocytopenia. Serum platelet antibodies were identified. A bone marrow biopsy showed small foci of metastatic breast cancer, thrombocytopenia, and normal number of megakaryocytes. A subsequent trial of steroids resulted in a marked improvement of the patient's thrombocytopenia. This is the fourth case report indicating an association of breast cancer and ITP.

Original languageEnglish (US)
Pages (from-to)411-413
Number of pages3
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume22
Issue number4
DOIs
StatePublished - Aug 1 1999

Keywords

  • Breast cancer
  • Idiopathic thrombocytopenic purpura
  • Thrombocytopenia

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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