Idiopathic inflammatory myopathy of the antisynthetase (Jo-1) type associated with noncaseating granulomas

K. G. Moder, T. A. Gaffey, Eric Lawrence Matteson

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The idiopathic inflammatory myopathies are a heterogeneous group of syndromes that share the finding of chronic muscle inflammation. Recently, serologic subtyping of autoantibodies found in patients with these syndromes has been used to identify distinct clinical entities. We describe a 36-year- old woman who, based on the findings of polymyositis documented by both electromyography and muscle biopsy, features of Raynaud's phenomenon, symmetric polyarthritis, 'mechanic's hands,' and Jo-1 antibody positivity, was considered to have the antisynthetase subset of idiopathic inflammatory myopathy. In addition, the patient had granulomatous synovitis, and noncaseating granulomas were found in a breast nodule. This is the first published report of granuloma formation in the antisynthetase syndrome.

Original languageEnglish (US)
Pages (from-to)1743-1747
Number of pages5
JournalArthritis and Rheumatism
Volume36
Issue number12
DOIs
StatePublished - 1993

Fingerprint

Myositis
Granuloma
Polymyositis
Muscles
Raynaud Disease
Synovitis
Electromyography
Autoantibodies
Arthritis
Breast
Hand
Inflammation
Biopsy
Jo-1 antibody
Antisynthetase syndrome

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Idiopathic inflammatory myopathy of the antisynthetase (Jo-1) type associated with noncaseating granulomas. / Moder, K. G.; Gaffey, T. A.; Matteson, Eric Lawrence.

In: Arthritis and Rheumatism, Vol. 36, No. 12, 1993, p. 1743-1747.

Research output: Contribution to journalArticle

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