Identifying the Stroma as a Critical Player in Radiation-Induced Mammary Tumor Development

Magdalena A. Cichon, Evette S Radisky, Derek C Radisky

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Tumor development requires facilitative alterations in the stroma. In this issue of Cancer Cell, Nguyen et al. provide evidence that irradiation of mammary stroma drives accelerated development of mammary tumors that are more likely to be estrogen receptor-negative and implicate stromal production of transforming growth factor-β in this process.

Original languageEnglish (US)
Pages (from-to)571-572
Number of pages2
JournalCancer Cell
Volume19
Issue number5
DOIs
StatePublished - May 17 2011

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ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Oncology

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