Abstract
The purpose of our study was to examine the ability of clinical and resting electrocardiographic variables to provide useful estimates of the probability of three-vessel or left-main coronary artery disease. The study group consisted of 680 patients with symptomatic coronary artery disease who underwent exercise equilibrium radionuclide angiography and coronary angiography within 6 months. Sixteen clinical and electrocardiographic variables were examined by logistic regression analysis. The independently predictive variables were then used to develop convenient graphic estimates of the probability of three-vessel or left-main disease and to classify patients into high-risk (>35%), intermediate-risk (15-35%), or low-risk (<15%) groups. Five variables were independently predictive of left-main or three-vessel disease: age, typical angina, diabetes, gender, and both history and electrocardiographic evidence of a prior myocardial infarction. A single graph was constructed that displayed the probability of severe coronary artery disease as a function of a five-point cardiac risk scale, which incorporated these variables. Two hundred sixty-two patients (39% of the study group) were classified as high risk; 127 of these patients (48%) had three-vessel or left-main disease. An additional 96 patients were classified as low risk; nine of these patients (9%) had three-vessel or left main disease. Five clinical variables that were obtained on an initial patient assessment can provide useful estimates of the likelihood of severe coronary disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 309-312 |
| Number of pages | 4 |
| Journal | Archives of Internal Medicine |
| Volume | 152 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1992 |
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ASJC Scopus subject areas
- Internal Medicine
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Identification of severe coronary artery disease using simple clinical parameters. / Hubbard, B. L.; Gibbons, Raymond J; Lapeyre, A. C.; Zinsmeister, A. R.; Clements, I. P.
In: Archives of Internal Medicine, Vol. 152, No. 2, 1992, p. 309-312.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Identification of severe coronary artery disease using simple clinical parameters
AU - Hubbard, B. L.
AU - Gibbons, Raymond J
AU - Lapeyre, A. C.
AU - Zinsmeister, A. R.
AU - Clements, I. P.
PY - 1992
Y1 - 1992
N2 - The purpose of our study was to examine the ability of clinical and resting electrocardiographic variables to provide useful estimates of the probability of three-vessel or left-main coronary artery disease. The study group consisted of 680 patients with symptomatic coronary artery disease who underwent exercise equilibrium radionuclide angiography and coronary angiography within 6 months. Sixteen clinical and electrocardiographic variables were examined by logistic regression analysis. The independently predictive variables were then used to develop convenient graphic estimates of the probability of three-vessel or left-main disease and to classify patients into high-risk (>35%), intermediate-risk (15-35%), or low-risk (<15%) groups. Five variables were independently predictive of left-main or three-vessel disease: age, typical angina, diabetes, gender, and both history and electrocardiographic evidence of a prior myocardial infarction. A single graph was constructed that displayed the probability of severe coronary artery disease as a function of a five-point cardiac risk scale, which incorporated these variables. Two hundred sixty-two patients (39% of the study group) were classified as high risk; 127 of these patients (48%) had three-vessel or left-main disease. An additional 96 patients were classified as low risk; nine of these patients (9%) had three-vessel or left main disease. Five clinical variables that were obtained on an initial patient assessment can provide useful estimates of the likelihood of severe coronary disease.
AB - The purpose of our study was to examine the ability of clinical and resting electrocardiographic variables to provide useful estimates of the probability of three-vessel or left-main coronary artery disease. The study group consisted of 680 patients with symptomatic coronary artery disease who underwent exercise equilibrium radionuclide angiography and coronary angiography within 6 months. Sixteen clinical and electrocardiographic variables were examined by logistic regression analysis. The independently predictive variables were then used to develop convenient graphic estimates of the probability of three-vessel or left-main disease and to classify patients into high-risk (>35%), intermediate-risk (15-35%), or low-risk (<15%) groups. Five variables were independently predictive of left-main or three-vessel disease: age, typical angina, diabetes, gender, and both history and electrocardiographic evidence of a prior myocardial infarction. A single graph was constructed that displayed the probability of severe coronary artery disease as a function of a five-point cardiac risk scale, which incorporated these variables. Two hundred sixty-two patients (39% of the study group) were classified as high risk; 127 of these patients (48%) had three-vessel or left-main disease. An additional 96 patients were classified as low risk; nine of these patients (9%) had three-vessel or left main disease. Five clinical variables that were obtained on an initial patient assessment can provide useful estimates of the likelihood of severe coronary disease.
UR - http://www.scopus.com/inward/record.url?scp=0026581066&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026581066&partnerID=8YFLogxK
U2 - 10.1001/archinte.152.2.309
DO - 10.1001/archinte.152.2.309
M3 - Article
C2 - 1739359
AN - SCOPUS:0026581066
VL - 152
SP - 309
EP - 312
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 2
ER -