TY - JOUR
T1 - Identification of patients best suited for combined liver-kidney transplantation
T2 - Part II
AU - Davis, Connie L.
AU - Gonwa, Thomas A.
AU - Wilkinson, Alan H.
PY - 2002
Y1 - 2002
N2 - Liver-kidney transplantation (LKT) should be reserved for those recipients with primary disease affecting both organs. However, increasing transplant list waiting times have increased the development and duration of acute renal failure before liver transplantation. Furthermore, the need for posttransplant calcineurin inhibitors can render healing from acute renal failure difficult. Because of the increasing requests for and controversy over the topic of a kidney with a liver transplant (OLT) when complete failure of the kidney is not known, the following article will review the impact of renal failure on liver transplant outcome, treatment of peri-OLT renal failure, rejection rates after LKT, survival after LKT, and information on renal histology and progression of disease into the beginnings of an algorithm for making a decision about combined LKT.
AB - Liver-kidney transplantation (LKT) should be reserved for those recipients with primary disease affecting both organs. However, increasing transplant list waiting times have increased the development and duration of acute renal failure before liver transplantation. Furthermore, the need for posttransplant calcineurin inhibitors can render healing from acute renal failure difficult. Because of the increasing requests for and controversy over the topic of a kidney with a liver transplant (OLT) when complete failure of the kidney is not known, the following article will review the impact of renal failure on liver transplant outcome, treatment of peri-OLT renal failure, rejection rates after LKT, survival after LKT, and information on renal histology and progression of disease into the beginnings of an algorithm for making a decision about combined LKT.
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U2 - 10.1053/jlts.2002.32504
DO - 10.1053/jlts.2002.32504
M3 - Article
C2 - 11910564
AN - SCOPUS:0036201160
SN - 1527-6465
VL - 8
SP - 193
EP - 211
JO - Liver Transplantation
JF - Liver Transplantation
IS - 3
ER -