TY - JOUR
T1 - Identification and cloning of the G3B cDNA encoding a 3′ segment of a protein binding to GATA-3
AU - Shapiro, Virginia Smith
AU - Lee, Perry
AU - Winoto, Astar
PY - 1995/10/3
Y1 - 1995/10/3
N2 - The transcription factor GATA-3 contributes to the expression of several genes critical for T-cell function and development, including the T-cell receptor α and β chains. We report here the isolation of a human cDNA clone which encodes a 3′ segment of a novel protein with three zinc fingers. This protein, which we termed G3B, can interact with GATA-3 in vitro. Its mRNA is expressed in T and B cells. Thus, G3B may represent a potential regulator of GATA-3 function.
AB - The transcription factor GATA-3 contributes to the expression of several genes critical for T-cell function and development, including the T-cell receptor α and β chains. We report here the isolation of a human cDNA clone which encodes a 3′ segment of a novel protein with three zinc fingers. This protein, which we termed G3B, can interact with GATA-3 in vitro. Its mRNA is expressed in T and B cells. Thus, G3B may represent a potential regulator of GATA-3 function.
KW - Recombinant DNA
KW - T-cell receptor
KW - transcription factor
KW - zinc finger
UR - http://www.scopus.com/inward/record.url?scp=0028843649&partnerID=8YFLogxK
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U2 - 10.1016/0378-1119(95)00420-B
DO - 10.1016/0378-1119(95)00420-B
M3 - Article
C2 - 7590293
AN - SCOPUS:0028843649
SN - 0378-1119
VL - 163
SP - 329
EP - 330
JO - Gene
JF - Gene
IS - 2
ER -