Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia

M. C. Brodsky, J. P. Frindik

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.

Original languageEnglish (US)
Pages (from-to)747-748
Number of pages2
JournalAmerican journal of ophthalmology
Volume122
Issue number5
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Ophthalmology

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