Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia

M. C. Brodsky; J. P. Frindik

doi:10.1016/S0002-9394(14)70505-7

Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia

M. C. Brodsky, J. P. Frindik

Ophthalmology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.

Original language	English (US)
Pages (from-to)	747-748
Number of pages	2
Journal	American journal of ophthalmology
Volume	122
Issue number	5
DOIs	https://doi.org/10.1016/S0002-9394(14)70505-7
State	Published - 1996

ASJC Scopus subject areas

Ophthalmology

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@article{a839d14c13cc4a59a787b9b65e990715,

title = "Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia",

abstract = "PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.",

author = "Brodsky, {M. C.} and Frindik, {J. P.}",

note = "Funding Information: Departments of Ophthalmology (M.C.B.) and Pediatrics (M.C.B., J.P.F.), University of Arkansas for Medical Sciences. Supported in part by a grant from Research to Prevent Blindness, Ine, New York, New York.",

year = "1996",

doi = "10.1016/S0002-9394(14)70505-7",

language = "English (US)",

volume = "122",

pages = "747--748",

journal = "American journal of ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "5",

}

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T1 - Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia

AU - Brodsky, M. C.

AU - Frindik, J. P.

N1 - Funding Information: Departments of Ophthalmology (M.C.B.) and Pediatrics (M.C.B., J.P.F.), University of Arkansas for Medical Sciences. Supported in part by a grant from Research to Prevent Blindness, Ine, New York, New York.

PY - 1996

Y1 - 1996

N2 - PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.

AB - PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies.

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JO - American journal of ophthalmology

JF - American journal of ophthalmology

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ER -

Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia

Abstract

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