Hypothalamic hamartoma with neurofibrillary tangles

Seiji Yamada, Christopher P. Wood, Jawad A. Shah, Jonathan Vida, Joseph E Parisi, Mark E. Jentoft

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hypothalamic hamartomas are rare tumors that typically present in childhood, often with gelastic seizures, precocious puberty, or as a manifestation of Pallister‑Hall syndrome. Neurofibrillary tangles are cytoplasmic aggregates of hyperphosphorylated tau that are best recognized in Alzheimer disease, other tau-associated neurodegenerative diseases, or as part of aging, but occasionally may be seen in low-grade neoplasms with a ganglion cell component as gangliocytoma or ganglioglioma. Herein, we report a case of hypothalamic hamartoma with neurofibrillary tangles.

Original languageEnglish (US)
Pages (from-to)480-484
Number of pages5
JournalNeuropathology
Volume36
Issue number5
DOIs
StatePublished - Oct 1 2016

Fingerprint

Neurofibrillary Tangles
Ganglioglioma
Laughter
Ganglioneuroma
Precocious Puberty
Cellular Structures
Ganglia
Neurodegenerative Diseases
Neoplasms
Alzheimer Disease
Seizures
Hypothalamic hamartomas

Keywords

  • gangliocytoma
  • ganglioglioma
  • hypothalamic hamartoma
  • neurofibrillary tangle
  • tau

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Yamada, S., Wood, C. P., Shah, J. A., Vida, J., Parisi, J. E., & Jentoft, M. E. (2016). Hypothalamic hamartoma with neurofibrillary tangles. Neuropathology, 36(5), 480-484. https://doi.org/10.1111/neup.12296

Hypothalamic hamartoma with neurofibrillary tangles. / Yamada, Seiji; Wood, Christopher P.; Shah, Jawad A.; Vida, Jonathan; Parisi, Joseph E; Jentoft, Mark E.

In: Neuropathology, Vol. 36, No. 5, 01.10.2016, p. 480-484.

Research output: Contribution to journalArticle

Yamada, S, Wood, CP, Shah, JA, Vida, J, Parisi, JE & Jentoft, ME 2016, 'Hypothalamic hamartoma with neurofibrillary tangles', Neuropathology, vol. 36, no. 5, pp. 480-484. https://doi.org/10.1111/neup.12296
Yamada S, Wood CP, Shah JA, Vida J, Parisi JE, Jentoft ME. Hypothalamic hamartoma with neurofibrillary tangles. Neuropathology. 2016 Oct 1;36(5):480-484. https://doi.org/10.1111/neup.12296
Yamada, Seiji ; Wood, Christopher P. ; Shah, Jawad A. ; Vida, Jonathan ; Parisi, Joseph E ; Jentoft, Mark E. / Hypothalamic hamartoma with neurofibrillary tangles. In: Neuropathology. 2016 ; Vol. 36, No. 5. pp. 480-484.
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