Hyposplenism in primary systemic amyloidosis

M. A. Gertz; R. A. Kyle; P. R. Greipp

doi:10.7326/0003-4819-98-4-475

Hyposplenism in primary systemic amyloidosis

M. A. Gertz, R. A. Kyle, P. R. Greipp

Hematology

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37 Scopus citations

Abstract

Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p < 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.

Original language	English (US)
Pages (from-to)	475-477
Number of pages	3
Journal	Annals of internal medicine
Volume	98
Issue number	4
DOIs	https://doi.org/10.7326/0003-4819-98-4-475
State	Published - 1983

ASJC Scopus subject areas

Internal Medicine

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10.7326/0003-4819-98-4-475

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abstract = "Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p < 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.",

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AU - Kyle, R. A.

AU - Greipp, P. R.

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AB - Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p < 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.

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Hyposplenism in primary systemic amyloidosis

Abstract

ASJC Scopus subject areas

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