Abstract
In 1953, Poulsen described the remarkable case of a woman with type I diabetes mellitus who experienced resolution of her retinopathy following postpartum pituitary necrosis. Since that time, many investigators have pursued the hypothesis that anterior pituitary hormones, particularly growth hormone, play a role in the pathogenesis of the microvascular complications of diabetes mellitus. While most observers have demonstrated the importance of growth hormone in the initiation and progression of diabetic retinopathy, the role of growth hormone in the development of diabetic nephropathy has been more difficult to document. In this case report, we describe a woman with long-standing type I diabetes mellitus complicated by retinopathy and nephropathy whose complications stabilized as she developed growth hormone deficiency.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 265-267 |
| Number of pages | 3 |
| Journal | American Journal of Nephrology |
| Volume | 12 |
| Issue number | 4 |
| State | Published - 1992 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Nephrology
Cite this
Hypopituitarism stabilizes the renal and retinal complications of diabetes mellitus. / Plumb, M.; Nath, Karl A; Seaquist, E. R.
In: American Journal of Nephrology, Vol. 12, No. 4, 1992, p. 265-267.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hypopituitarism stabilizes the renal and retinal complications of diabetes mellitus
AU - Plumb, M.
AU - Nath, Karl A
AU - Seaquist, E. R.
PY - 1992
Y1 - 1992
N2 - In 1953, Poulsen described the remarkable case of a woman with type I diabetes mellitus who experienced resolution of her retinopathy following postpartum pituitary necrosis. Since that time, many investigators have pursued the hypothesis that anterior pituitary hormones, particularly growth hormone, play a role in the pathogenesis of the microvascular complications of diabetes mellitus. While most observers have demonstrated the importance of growth hormone in the initiation and progression of diabetic retinopathy, the role of growth hormone in the development of diabetic nephropathy has been more difficult to document. In this case report, we describe a woman with long-standing type I diabetes mellitus complicated by retinopathy and nephropathy whose complications stabilized as she developed growth hormone deficiency.
AB - In 1953, Poulsen described the remarkable case of a woman with type I diabetes mellitus who experienced resolution of her retinopathy following postpartum pituitary necrosis. Since that time, many investigators have pursued the hypothesis that anterior pituitary hormones, particularly growth hormone, play a role in the pathogenesis of the microvascular complications of diabetes mellitus. While most observers have demonstrated the importance of growth hormone in the initiation and progression of diabetic retinopathy, the role of growth hormone in the development of diabetic nephropathy has been more difficult to document. In this case report, we describe a woman with long-standing type I diabetes mellitus complicated by retinopathy and nephropathy whose complications stabilized as she developed growth hormone deficiency.
UR - http://www.scopus.com/inward/record.url?scp=0026743352&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026743352&partnerID=8YFLogxK
M3 - Article
C2 - 1481875
AN - SCOPUS:0026743352
VL - 12
SP - 265
EP - 267
JO - American Journal of Nephrology
JF - American Journal of Nephrology
SN - 0250-8095
IS - 4
ER -