Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research

John P. Bilezikian, Aliya Khan, John T. Potts, Maria Luisa Brandi, Bart L. Clarke, Dolores Shoback, Harald Jüppner, Pierre D'Amour, John Fox, Lars Rejnmark, Leif Mosekilde, Mishaela R. Rubin, David Dempster, Rachel Gafni, Michael T. Collins, Jim Sliney, James Sanders

Research output: Contribution to journalReview article

260 Scopus citations

Abstract

Recent advances in understanding the epidemiology, genetics, diagnosis, clinical presentations, skeletal involvement, and therapeutic approaches to hypoparathyroidism led to the First International Workshop on Hypoparathyroidism that was held in 2009. At this conference, a group of experts convened to discuss these issues with a view towards a future research agenda for this disease. This review, which focuses primarily on hypoparathyroidism in the adult, provides a comprehensive summary of the latest information on this disease.

Original languageEnglish (US)
Pages (from-to)2317-2337
Number of pages21
JournalJournal of Bone and Mineral Research
Volume26
Issue number10
DOIs
StatePublished - Oct 1 2011

Keywords

  • calcium
  • epidemiology
  • genetics
  • hypocalcemia
  • hypoparathyroidism
  • parathyroid hormone

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine

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    Bilezikian, J. P., Khan, A., Potts, J. T., Brandi, M. L., Clarke, B. L., Shoback, D., Jüppner, H., D'Amour, P., Fox, J., Rejnmark, L., Mosekilde, L., Rubin, M. R., Dempster, D., Gafni, R., Collins, M. T., Sliney, J., & Sanders, J. (2011). Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. Journal of Bone and Mineral Research, 26(10), 2317-2337. https://doi.org/10.1002/jbmr.483