Hypoglycemia in the nondiabetic patient

Caroline J. Davidge-Pitts, Adrian Vella

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Under most physiologic conditions encountered in modern life, glucose is the brain's obligate fuel (Cryer, 117:868-870, 2007); therefore maintenance of blood glucose within the physiological range is of great importance. Hypoglycemic disorders, although uncommon (Service, J Clin Invest 332:1144-1152, 1995), are significant because low blood glucose leads to symptoms and signs of brain dysfunction. Profound or prolonged hypoglycemia may lead to cardiac arrhythmias, cognitive dysfunction or brain death (Cryer, N Eng J Med 117:868-870, 2007). However, the symptoms of hypoglycemia such as tachycardia, sweating, tremor, and nervousness are not specific to hypoglycemia. To diagnose a hypoglycemic disorder, it is necessary to document low blood glucose at the time of symptoms compatible with neuroglycopenia. These symptoms should be ameliorated by correction of the hypoglycemia. This is often referred to as Whipple's triad (Whipple, Can Med Assoc J 66:334-342, 1952) and such documentation must underpin the diagnosis of a hypoglycemic disorder. In this chapter, we discuss the important aspects of hypoglycemic disorders, including clinical presentation, differential diagnosis, evaluation, and treatment.

Original languageEnglish (US)
Title of host publicationEndocrinology and Diabetes: A Problem-Oriented Approach
PublisherSpringer New York
Pages419-428
Number of pages10
Volume9781461486848
ISBN (Print)9781461486848, 1461486831, 9781461486831
DOIs
StatePublished - Nov 1 2014

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Hypoglycemia
Hypoglycemic Agents
Blood Glucose
Brain Death
Sweating
Brain
Tremor
Tachycardia
Documentation
Signs and Symptoms
Cardiac Arrhythmias
Differential Diagnosis
Anxiety
Maintenance
Glucose
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Davidge-Pitts, C. J., & Vella, A. (2014). Hypoglycemia in the nondiabetic patient. In Endocrinology and Diabetes: A Problem-Oriented Approach (Vol. 9781461486848, pp. 419-428). Springer New York. https://doi.org/10.1007/978-1-4614-8684-8_33

Hypoglycemia in the nondiabetic patient. / Davidge-Pitts, Caroline J.; Vella, Adrian.

Endocrinology and Diabetes: A Problem-Oriented Approach. Vol. 9781461486848 Springer New York, 2014. p. 419-428.

Research output: Chapter in Book/Report/Conference proceedingChapter

Davidge-Pitts, CJ & Vella, A 2014, Hypoglycemia in the nondiabetic patient. in Endocrinology and Diabetes: A Problem-Oriented Approach. vol. 9781461486848, Springer New York, pp. 419-428. https://doi.org/10.1007/978-1-4614-8684-8_33
Davidge-Pitts CJ, Vella A. Hypoglycemia in the nondiabetic patient. In Endocrinology and Diabetes: A Problem-Oriented Approach. Vol. 9781461486848. Springer New York. 2014. p. 419-428 https://doi.org/10.1007/978-1-4614-8684-8_33
Davidge-Pitts, Caroline J. ; Vella, Adrian. / Hypoglycemia in the nondiabetic patient. Endocrinology and Diabetes: A Problem-Oriented Approach. Vol. 9781461486848 Springer New York, 2014. pp. 419-428
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