Hypertension in pregnancy: Is it time for a new approach to treatment?

Marvin Moser, Catherine M. Brown, Carl H. Rose, Vesna D. Garovic

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

Hypertensive disorders represent major causes of pregnancy-related maternal mortality worldwide. The current definition and treatment recommendations for elevated blood pressure (BP) during pregnancy in the United States have remained unchanged for many years, unlike the recommendations for hypertension treatment in the general population. Clinical studies have provided convincing evidence that women with hypertensive pregnancy disorders are at both immediate and long-term risk for cardiovascular complications; these findings suggest that consideration be given to lowering the presently recommended BP thresholds, both for the initiation of therapy and for therapeutic targets, and to simplifying the approach to the management of elevated BP in pregnancy. This review focuses on the current treatment strategies for hypertensive pregnancy disorders, new developments in the field of hypertension, in general, and in pregnant patients, in particular, and their potential impact on contemporary BP goals and the use of specific antihypertensive medications in pregnancy.

Original languageEnglish (US)
Pages (from-to)1092-1100
Number of pages9
JournalJournal of hypertension
Volume30
Issue number6
DOIs
StatePublished - Jun 2012

Keywords

  • antihypertensive therapy in pregnancy
  • cardiovascular complications
  • hypertension in pregnancy
  • pre-eclampsia

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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