Hyperglycemia during the immediate period following liver transplantation

K. Tuesday Werner, Patricia A. Mackey, Janna C. Castro, Elizabeth J. Carey, Harini M Chakkera, Curtiss B. Cook

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aim: High blood glucose levels in the hospital are common among transplant recipients. Methods: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). Results: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06-1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23-1.95; p < 0.01). Conclusion: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.

Original languageEnglish (US)
Article numberFSO97
JournalFuture Science OA
Volume2
Issue number1
DOIs
StatePublished - Mar 1 2016

Fingerprint

Hyperglycemia
Liver Transplantation
Diabetes Mellitus
Inpatients
Insulin
Liver
Self Care
Hypoglycemia
Blood Glucose
Glucose
Transplant Recipients

Keywords

  • diabetes mellitus
  • hospital
  • hyperglycemia
  • inpatient
  • liver transplant

ASJC Scopus subject areas

  • Biotechnology

Cite this

Werner, K. T., Mackey, P. A., Castro, J. C., Carey, E. J., Chakkera, H. M., & Cook, C. B. (2016). Hyperglycemia during the immediate period following liver transplantation. Future Science OA, 2(1), [FSO97]. https://doi.org/10.4155/fsoa-2015-0010

Hyperglycemia during the immediate period following liver transplantation. / Werner, K. Tuesday; Mackey, Patricia A.; Castro, Janna C.; Carey, Elizabeth J.; Chakkera, Harini M; Cook, Curtiss B.

In: Future Science OA, Vol. 2, No. 1, FSO97, 01.03.2016.

Research output: Contribution to journalArticle

Werner, K. Tuesday ; Mackey, Patricia A. ; Castro, Janna C. ; Carey, Elizabeth J. ; Chakkera, Harini M ; Cook, Curtiss B. / Hyperglycemia during the immediate period following liver transplantation. In: Future Science OA. 2016 ; Vol. 2, No. 1.
@article{c08e889611e549659ac8079133601259,
title = "Hyperglycemia during the immediate period following liver transplantation",
abstract = "Aim: High blood glucose levels in the hospital are common among transplant recipients. Methods: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). Results: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23{\%} for every 5-year age increase (odds ratio: 1.23; 95{\%} CI: 1.06-1.44; p = 0.007) and 51{\%} for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95{\%} CI: 1.23-1.95; p < 0.01). Conclusion: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.",
keywords = "diabetes mellitus, hospital, hyperglycemia, inpatient, liver transplant",
author = "Werner, {K. Tuesday} and Mackey, {Patricia A.} and Castro, {Janna C.} and Carey, {Elizabeth J.} and Chakkera, {Harini M} and Cook, {Curtiss B.}",
year = "2016",
month = "3",
day = "1",
doi = "10.4155/fsoa-2015-0010",
language = "English (US)",
volume = "2",
journal = "Future Science OA",
issn = "2056-5623",
publisher = "Future Medicine Ltd.",
number = "1",

}

TY - JOUR

T1 - Hyperglycemia during the immediate period following liver transplantation

AU - Werner, K. Tuesday

AU - Mackey, Patricia A.

AU - Castro, Janna C.

AU - Carey, Elizabeth J.

AU - Chakkera, Harini M

AU - Cook, Curtiss B.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Aim: High blood glucose levels in the hospital are common among transplant recipients. Methods: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). Results: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06-1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23-1.95; p < 0.01). Conclusion: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.

AB - Aim: High blood glucose levels in the hospital are common among transplant recipients. Methods: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). Results: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06-1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23-1.95; p < 0.01). Conclusion: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.

KW - diabetes mellitus

KW - hospital

KW - hyperglycemia

KW - inpatient

KW - liver transplant

UR - http://www.scopus.com/inward/record.url?scp=85058833818&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058833818&partnerID=8YFLogxK

U2 - 10.4155/fsoa-2015-0010

DO - 10.4155/fsoa-2015-0010

M3 - Article

AN - SCOPUS:85058833818

VL - 2

JO - Future Science OA

JF - Future Science OA

SN - 2056-5623

IS - 1

M1 - FSO97

ER -