Hyaluronic acid diminishes the resistance to excursion after flexor tendon repair: An in vitro biomechanical study

T. Akasaka; J. Nishida; S. Araki; T. Shimamura; P. C. Amadio; K. N. An

doi:10.1016/j.jbiomech.2004.04.021

Hyaluronic acid diminishes the resistance to excursion after flexor tendon repair: An in vitro biomechanical study

T. Akasaka, J. Nishida, S. Araki, T. Shimamura, P. C. Amadio, K. N. An

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Adhesion between the tendon and tendon sheath after primary flexor tendon repair is seen frequently, and postoperative finger function is occasionally unsatisfactory. A reduction of the friction may facilitate tendon mobilization, which in turn may reduce the risk of the adhesion and restriction of range of motion. We considered the possibility of utilizing the hyaluronic acid (HA) as a lubricant. To evaluate the effect of HA, the gliding resistance between the canine flexor digitorum profundus tendon repaired by a modified Kessler suture technique with running epitendinous suture and the annular pulley located on the proximal phalanx (corresponding to the A2 pulley in humans) was evaluated and compared before and after administration of HA. The HA solution measurement groups were identified as follows; intact tendon as a control; repaired tendon; tendon soaked in 0.1, 1, and 10mg/ml HA. The resistance increased after repairing, then it decreased after soaking in 10mg/ml HA solution. The results of this study revealed that HA diminishes the excursion resistance after flexor tendon repair. We believe that some style of administration of the HA might reduce the excursion resistance and prevent adhesion until the synovial surface is fully developed.

Original language	English (US)
Pages (from-to)	503-507
Number of pages	5
Journal	Journal of Biomechanics
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/j.jbiomech.2004.04.021
State	Published - Mar 2005

Keywords

Gliding resistance
Hyaluronic acid
Tenorrhaphy

ASJC Scopus subject areas

Biophysics
Orthopedics and Sports Medicine
Biomedical Engineering
Rehabilitation

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title = "Hyaluronic acid diminishes the resistance to excursion after flexor tendon repair: An in vitro biomechanical study",

abstract = "Adhesion between the tendon and tendon sheath after primary flexor tendon repair is seen frequently, and postoperative finger function is occasionally unsatisfactory. A reduction of the friction may facilitate tendon mobilization, which in turn may reduce the risk of the adhesion and restriction of range of motion. We considered the possibility of utilizing the hyaluronic acid (HA) as a lubricant. To evaluate the effect of HA, the gliding resistance between the canine flexor digitorum profundus tendon repaired by a modified Kessler suture technique with running epitendinous suture and the annular pulley located on the proximal phalanx (corresponding to the A2 pulley in humans) was evaluated and compared before and after administration of HA. The HA solution measurement groups were identified as follows; intact tendon as a control; repaired tendon; tendon soaked in 0.1, 1, and 10mg/ml HA. The resistance increased after repairing, then it decreased after soaking in 10mg/ml HA solution. The results of this study revealed that HA diminishes the excursion resistance after flexor tendon repair. We believe that some style of administration of the HA might reduce the excursion resistance and prevent adhesion until the synovial surface is fully developed.",

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author = "T. Akasaka and J. Nishida and S. Araki and T. Shimamura and Amadio, {P. C.} and An, {K. N.}",

note = "Funding Information: This study was supported by Grants-in-Aid for Scientific Research from The Japanese Ministry of Education, Science, Sports and Culture (No. 09671514 and 13671538).",

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doi = "10.1016/j.jbiomech.2004.04.021",

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T1 - Hyaluronic acid diminishes the resistance to excursion after flexor tendon repair

T2 - An in vitro biomechanical study

AU - Akasaka, T.

AU - Nishida, J.

AU - Araki, S.

AU - Shimamura, T.

AU - Amadio, P. C.

AU - An, K. N.

N1 - Funding Information: This study was supported by Grants-in-Aid for Scientific Research from The Japanese Ministry of Education, Science, Sports and Culture (No. 09671514 and 13671538).

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N2 - Adhesion between the tendon and tendon sheath after primary flexor tendon repair is seen frequently, and postoperative finger function is occasionally unsatisfactory. A reduction of the friction may facilitate tendon mobilization, which in turn may reduce the risk of the adhesion and restriction of range of motion. We considered the possibility of utilizing the hyaluronic acid (HA) as a lubricant. To evaluate the effect of HA, the gliding resistance between the canine flexor digitorum profundus tendon repaired by a modified Kessler suture technique with running epitendinous suture and the annular pulley located on the proximal phalanx (corresponding to the A2 pulley in humans) was evaluated and compared before and after administration of HA. The HA solution measurement groups were identified as follows; intact tendon as a control; repaired tendon; tendon soaked in 0.1, 1, and 10mg/ml HA. The resistance increased after repairing, then it decreased after soaking in 10mg/ml HA solution. The results of this study revealed that HA diminishes the excursion resistance after flexor tendon repair. We believe that some style of administration of the HA might reduce the excursion resistance and prevent adhesion until the synovial surface is fully developed.

AB - Adhesion between the tendon and tendon sheath after primary flexor tendon repair is seen frequently, and postoperative finger function is occasionally unsatisfactory. A reduction of the friction may facilitate tendon mobilization, which in turn may reduce the risk of the adhesion and restriction of range of motion. We considered the possibility of utilizing the hyaluronic acid (HA) as a lubricant. To evaluate the effect of HA, the gliding resistance between the canine flexor digitorum profundus tendon repaired by a modified Kessler suture technique with running epitendinous suture and the annular pulley located on the proximal phalanx (corresponding to the A2 pulley in humans) was evaluated and compared before and after administration of HA. The HA solution measurement groups were identified as follows; intact tendon as a control; repaired tendon; tendon soaked in 0.1, 1, and 10mg/ml HA. The resistance increased after repairing, then it decreased after soaking in 10mg/ml HA solution. The results of this study revealed that HA diminishes the excursion resistance after flexor tendon repair. We believe that some style of administration of the HA might reduce the excursion resistance and prevent adhesion until the synovial surface is fully developed.

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KW - Hyaluronic acid

KW - Tenorrhaphy

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Hyaluronic acid diminishes the resistance to excursion after flexor tendon repair: An in vitro biomechanical study

Abstract

Keywords

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