Huntingtin's critical cleavage

John D. Fryer, Huda Y. Zoghbi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The early pathogenic events leading to neurodegeneration in Huntington disease are not clear. A recent paper shows that mutating a caspase-6 cleavage site in the huntingtin protein is sufficient to prevent pathogenesis.

Original languageEnglish (US)
Pages (from-to)1088-1089
Number of pages2
JournalNature Neuroscience
Volume9
Issue number9
DOIs
StatePublished - Sep 2006
Externally publishedYes

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Caspase 6
Huntington Disease
Huntingtin Protein

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Huntingtin's critical cleavage. / Fryer, John D.; Zoghbi, Huda Y.

In: Nature Neuroscience, Vol. 9, No. 9, 09.2006, p. 1088-1089.

Research output: Contribution to journalArticle

Fryer, John D. ; Zoghbi, Huda Y. / Huntingtin's critical cleavage. In: Nature Neuroscience. 2006 ; Vol. 9, No. 9. pp. 1088-1089.
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