Human gene therapy vectors derived from feline lentiviruses

Román A. Barraza, Eric M. Poeschla

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Lentiviral vectors are useful for gene transfer to dividing and nondividing cells. Feline immunodeficiency virus (FIV) vectors transduce most human cell types with good efficiency and may have advantages for clinical gene therapy applications. This article reviews significant progress in the development and refinement of FIV vector systems.

Original languageEnglish (US)
Pages (from-to)23-31
Number of pages9
JournalVeterinary Immunology and Immunopathology
Volume123
Issue number1-2
DOIs
StatePublished - May 15 2008

Keywords

  • Feline immunodeficiency virus
  • Gene therapy
  • Innate immunity
  • Retroviral vectors

ASJC Scopus subject areas

  • Immunology
  • veterinary(all)

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