How many women have osteoporosis?

L. Joseph Melton, Elizabeth A. Chrischilles, Cyrus Cooper, Ann W. Lane, B. Lawrence Riggs

Research output: Contribution to journalArticle

1100 Citations (Scopus)

Abstract

Osteoporosis is widely viewed as a major public health concern, but the exact magnitude of the problem is uncertain and likely to depend on how the condition is defined. Noninvasive bone mineral measurements can be used to define a state of heightened fracture risk (osteopenia), or the ultimate clinical manifestation of fracture can be assessed (established osteoporosis). If bone mineral measurements more than 2 standard deviations below the mean of young normal women represent osteopenia, then 45% of white women aged 50 years and over have the condition at one or more sites in the hip, spine, or forearm on the basis of population-based data from Rochester, Minnesota. A smaller proportion is affected at each specific skeletal site: 32% have bone mineral values this low in the lumbar spine, 29% in either of two regions in the proximal femur, and 26% in the midradius. Although this overall estimate is substantial, some other serious chronic diseases are almost as common. More importantly, low bone mass is associated with adverse health outcomes, especially fractures. The lifetime risk of any fracture of the hip, spine, or distal forearm is almost 40% in white women and 13% in white men from age 50 years onward. If the enormous costs associated with these fractures are to be reduced, increased attention must be given to the design and implementation of control programs directed at this major health problem.

Original languageEnglish (US)
Pages (from-to)1005-1010
Number of pages6
JournalJournal of Bone and Mineral Research
Volume7
Issue number9
StatePublished - Sep 1992

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Osteoporosis
Minerals
Bone and Bones
Spine
Metabolic Bone Diseases
Forearm
Health
Hip Fractures
Femur
Hip
Chronic Disease
Public Health
Costs and Cost Analysis
Population

ASJC Scopus subject areas

  • Surgery

Cite this

Melton, L. J., Chrischilles, E. A., Cooper, C., Lane, A. W., & Riggs, B. L. (1992). How many women have osteoporosis? Journal of Bone and Mineral Research, 7(9), 1005-1010.

How many women have osteoporosis? / Melton, L. Joseph; Chrischilles, Elizabeth A.; Cooper, Cyrus; Lane, Ann W.; Riggs, B. Lawrence.

In: Journal of Bone and Mineral Research, Vol. 7, No. 9, 09.1992, p. 1005-1010.

Research output: Contribution to journalArticle

Melton, LJ, Chrischilles, EA, Cooper, C, Lane, AW & Riggs, BL 1992, 'How many women have osteoporosis?', Journal of Bone and Mineral Research, vol. 7, no. 9, pp. 1005-1010.
Melton LJ, Chrischilles EA, Cooper C, Lane AW, Riggs BL. How many women have osteoporosis? Journal of Bone and Mineral Research. 1992 Sep;7(9):1005-1010.
Melton, L. Joseph ; Chrischilles, Elizabeth A. ; Cooper, Cyrus ; Lane, Ann W. ; Riggs, B. Lawrence. / How many women have osteoporosis?. In: Journal of Bone and Mineral Research. 1992 ; Vol. 7, No. 9. pp. 1005-1010.
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