How do cells sense a transcellular pressure difference? a combined computational and experimental approach

Anna McVittie, Daniel Tschumperlin, Jeffery Drazen, Roger Kamm

Research output: Contribution to journalConference articlepeer-review

Abstract

Mitogen activated protein (MAP) kinases were activated by a number of stimuli. Among the three known MAP kinase family members, extracellular signal-related kinase (ERK) was strongly activated in the transepithelial pressure system after one minute (30cmH20), with the response peaking at five minutes. Little or no response was seen in the p38 or c-jun N terminal MAP kinases.

Original languageEnglish (US)
Pages (from-to)S-90
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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