Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades

Nour Zleik; Mohanad M. Elfishawi; Zoran Kvrgic; Clement J. Michet; Cynthia S. Crowson; Eric L. Matteson; Tim Bongartz

doi:10.3899/jrheum.171320

Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades

Nour Zleik, Mohanad M. Elfishawi, Zoran Kvrgic, Clement J. Michet, Cynthia S. Crowson, Eric L. Matteson, Tim Bongartz

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Objective: To assess in-hospital gout flares in patients with gout. Methods: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. Results: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion. Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.

Original language	English (US)
Pages (from-to)	1188-1191
Number of pages	4
Journal	Journal of Rheumatology
Volume	45
Issue number	8
DOIs	https://doi.org/10.3899/jrheum.171320
State	Published - Aug 1 2018

Keywords

Gout
Healthcare Use
Hospitalization
Hyperuricemia

ASJC Scopus subject areas

Rheumatology
Immunology and Allergy
Immunology

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10.3899/jrheum.171320

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title = "Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades",

abstract = "Objective: To assess in-hospital gout flares in patients with gout. Methods: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. Results: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion. Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.",

keywords = "Gout, Healthcare Use, Hospitalization, Hyperuricemia",

author = "Nour Zleik and Elfishawi, {Mohanad M.} and Zoran Kvrgic and Michet, {Clement J.} and Crowson, {Cynthia S.} and Matteson, {Eric L.} and Tim Bongartz",

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doi = "10.3899/jrheum.171320",

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T2 - A population-based study over 2 decades

AU - Zleik, Nour

AU - Elfishawi, Mohanad M.

AU - Kvrgic, Zoran

AU - Michet, Clement J.

AU - Crowson, Cynthia S.

AU - Matteson, Eric L.

AU - Bongartz, Tim

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Objective: To assess in-hospital gout flares in patients with gout. Methods: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. Results: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion. Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.

AB - Objective: To assess in-hospital gout flares in patients with gout. Methods: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. Results: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion. Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.

KW - Gout

KW - Healthcare Use

KW - Hospitalization

KW - Hyperuricemia

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Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades

Abstract

Keywords

ASJC Scopus subject areas

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