Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades

Nour Zleik, Mohanad M. Elfishawi, Zoran Kvrgic, Clement Michet, Cynthia Crowson, Eric Lawrence Matteson, Tim Bongartz

Research output: Contribution to journalArticle

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Objective: To assess in-hospital gout flares in patients with gout. Methods: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. Results: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). Conclusion. Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.

Original languageEnglish (US)
Pages (from-to)1188-1191
Number of pages4
JournalJournal of Rheumatology
Issue number8
StatePublished - Aug 1 2018



  • Gout
  • Healthcare Use
  • Hospitalization
  • Hyperuricemia

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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