History of carotid surgery: From ancient Greeks to the modern era

Tiziano Tallarita, Maurizio Gerbino, Carmelina Gurrieri, Giuseppe Lanzino

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A relationship between decreased carotid arterial flow and apoplectic manifestations was already suspected by the ancient Greeks. Early attempts at carotid surgery, however, were limited to emergency arterial ligation in patients with neck trauma. Attempts to suture arterial stumps together to restore blood flow paved the way for Carrel's revolutionary idea of reconstructing the resected or injured arterial segment with an interposition vein graft. DeBakey and Eastcott were the first to perform carotid endarterectomy in North America and the United Kingdom, respectively. In 1959, DeBakey proposed a cooperative study to assess the effectiveness of carotid endarterectomy in the treatment and prevention of ischemic cerebrovascular disease. The study was officially designated the Joint Study of Extracranial Arterial Occlusion and represented the first trial in the United States in which large numbers of patients were randomly allocated to surgical or nonsurgical therapy.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
JournalPerspectives in Vascular Surgery and Endovascular Therapy
Volume25
Issue number3-4
DOIs
StatePublished - Dec 2013

Keywords

  • carotid endarterectomy
  • carotid surgical history
  • stroke
  • transient ischemic attack

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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