History, Molecular Mechanisms, and Endoscopic Treatment of Barrett's Esophagus

Stuart Jon Spechler, Rebecca C. Fitzgerald, Ganapathy A. Prasad, Kenneth K. Wang

Research output: Contribution to journalReview article

135 Scopus citations

Abstract

This report is an adjunct to the American Gastroenterological Association Institute's medical position statement and technical review on the management of Barrett's esophagus, which will be published in the near future. Those documents will consider a number of broad questions on the diagnosis, clinical features, and management of patients with Barrett's esophagus, and the reader is referred to the technical review for an in-depth discussion of those topics. In this report, we review historical, molecular, and endoscopic therapeutic aspects of Barrett's esophagus that are of interest to clinicians and researchers.

Original languageEnglish (US)
Pages (from-to)854-869
Number of pages16
JournalGastroenterology
Volume138
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • Esophageal Neoplasms
  • Gastroesophageal Reflux
  • Gene Expression Regulation

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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