Historical perspective and clinical implications of the Pelger-Huet cell

John M. Cunningham, Mrinal M Patnaik, Dale E. Hammerschmidt, Gregory M. Vercellotti

Research output: Contribution to journalReview article

33 Citations (Scopus)

Abstract

The unique historical aspects of Pelger and Huet's discovery of the Pelger-Huet cell highlight the diagnostic challenge that this morphologic finding presents to the physician. Making the diagnosis of the benign autosomal dominant anomaly is complicated by the morphologically similar pseudo-Pelger-Huet cell, which can signify underlying myeloid dsyplasia. This article relates the history of the Pelger-Huet anomaly as well as describes the clinical significance and diagnostic workup for the finding of a Pelger-Huet cell on peripheral smear.

Original languageEnglish (US)
Pages (from-to)116-119
Number of pages4
JournalAmerican Journal of Hematology
Volume84
Issue number2
DOIs
StatePublished - Feb 2009

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Pelger-Huet Anomaly
History
Physicians

ASJC Scopus subject areas

  • Hematology

Cite this

Historical perspective and clinical implications of the Pelger-Huet cell. / Cunningham, John M.; Patnaik, Mrinal M; Hammerschmidt, Dale E.; Vercellotti, Gregory M.

In: American Journal of Hematology, Vol. 84, No. 2, 02.2009, p. 116-119.

Research output: Contribution to journalReview article

Cunningham, John M. ; Patnaik, Mrinal M ; Hammerschmidt, Dale E. ; Vercellotti, Gregory M. / Historical perspective and clinical implications of the Pelger-Huet cell. In: American Journal of Hematology. 2009 ; Vol. 84, No. 2. pp. 116-119.
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