Histopathology of iatrogenic injury in the colorectum

Dora Lam-Himlin, Christina A. Arnold, Elizabeth A. Montgomery

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Medical interventions may cause histologic changes and injury to the colorectal mucosa. Many of these changes overlap with one another and with medical gastrointestinal disease, such as inflammatory bowel disease. This review focuses on common causes of iatrogenic injury and the histologic patterns seen on mucosal biopsies. Topics covered include: 1. Endoscopy-induced artefacts, including mucosal pseudolipomatosis, pneumatosis coli, crush and cautery artefacts, and disinfectant colitis; 2. Changes induced by surgery and other therapies, including diversion colitis, radiation colitis, and graft versus host disease; and 3. Changes induced by drugs and toxins, including melanosis coli, chemotherapy, non-steroidal-anti-inflammatory drugs, mycophenolate, kayexalate, and bowel preparations.

Original languageEnglish (US)
Pages (from-to)404-408
Number of pages5
JournalDiagnostic Histopathology
Volume17
Issue number9
DOIs
StatePublished - Sep 2011

Fingerprint

Colitis
Artifacts
Wounds and Injuries
Cautery
Melanosis
Disinfectants
Gastrointestinal Diseases
Graft vs Host Disease
Inflammatory Bowel Diseases
Pharmaceutical Preparations
Endoscopy
Mucous Membrane
Anti-Inflammatory Agents
Radiation
Biopsy
Drug Therapy
Therapeutics

Keywords

  • Artefacts
  • Colitis
  • Drug induced
  • Endoscopy
  • Iatrogenic
  • Pathology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

Histopathology of iatrogenic injury in the colorectum. / Lam-Himlin, Dora; Arnold, Christina A.; Montgomery, Elizabeth A.

In: Diagnostic Histopathology, Vol. 17, No. 9, 09.2011, p. 404-408.

Research output: Contribution to journalArticle

Lam-Himlin, D, Arnold, CA & Montgomery, EA 2011, 'Histopathology of iatrogenic injury in the colorectum', Diagnostic Histopathology, vol. 17, no. 9, pp. 404-408. https://doi.org/10.1016/j.mpdhp.2011.06.015
Lam-Himlin, Dora ; Arnold, Christina A. ; Montgomery, Elizabeth A. / Histopathology of iatrogenic injury in the colorectum. In: Diagnostic Histopathology. 2011 ; Vol. 17, No. 9. pp. 404-408.
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