Abstract
The Theiler's virus model shows all the major features of MS pathology - demyelination, inflammation, axonal injury, and remyelination. Extensive qualitative and quantitative characterization of the pathology has provided important insights into disease mechanisms, particularly how they relate to neurological function.
| Original language | English (US) |
|---|---|
| Title of host publication | Experimental Models of Multiple Sclerosis |
| Publisher | Springer US |
| Pages | 579-591 |
| Number of pages | 13 |
| ISBN (Electronic) | 9780387255187 |
| ISBN (Print) | 0387255176, 9780387255170 |
| DOIs | |
| State | Published - 2005 |
Keywords
- Theiler's virus
- demyelination
- histopathology
- multiple sclerosis
ASJC Scopus subject areas
- General Medicine
- General Immunology and Microbiology