Histopathologic findings in primary erythromelalgia are nonspecific: Special studies show a decrease in small nerve fiber density

Mark D.P. Davis, Roger H. Weenig, Joseph Genebriera, Gwen Wendelschafer-Crabb, William R. Kennedy, Paola Sandroni

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

The histopathology of primary erythromelalgia has been poorly characterized. A total of 33 skin biopsy specimens from 29 patients with a diagnosis of primary erythromelalgia were re-examined. Histopathologic findings were nonspecific. Vascular thrombi were not identified. A relative decrease in small nerve fiber density was noted in specimens from 13 of 16 patients.

Original languageEnglish (US)
Pages (from-to)519-522
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume55
Issue number3
DOIs
StatePublished - Sep 2006

ASJC Scopus subject areas

  • Dermatology

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