Histologic and biomolecular similarities in healing between aneurysms and cutaneous skin wounds

J. R. Ayers-Ringler, Z. Khashim, Y. H. Ding, D. F. Kallmes, R. Kadirvel

Research output: Contribution to journalArticle

Abstract

The poorly understood mechanisms of aneurysm healing contribute substantially to the pressing medical problem of coiled aneurysm recanalization. Using an established saccular aneurysm model, we developed an animal model system in rabbits to study aneurysm and skin wound healing concurrently in the same animal. We found treated aneurysm healing to be similar to skin wound healing both histologically and in biomarker gene and protein expression, but in a delayed fashion.

Original languageEnglish (US)
Pages (from-to)1018-1021
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume40
Issue number6
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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