Hip avascular necrosis: Overview

Matthew T. Houdek, John R. Martin, Rafael J. Sierra

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Avascular necrosis (AVN) of the femoral head is a progressive disease that predominantly affects younger patients. The disease is characterized by a vascular insult to the femoral head blood supply, which can lead to collapse of the femoral head and subsequent degenerative changes. The exact pathophysiology underlying AVN has yet to be elucidated, although a number of risk factors have been determined. The diagnosis of AVN is commonly made based on clinical and radiological findings. Radiographs are initially performed; however, MRI has become the gold standard for diagnosis and has proven beneficial in staging patients. Most surgeons attempt to diagnose and treat AVN in the early stages, prior to collapse of the femoral head. There are a number of nonoperative and operative treatments that have been investigated for early stage AVN. Nonoperative modalities include statins, stanozolol, and bisphosphonates. Operative treatments include core decompression alone, core decompression with injection of bone marrow aspirate, or placement of some form of bone substitute and osteotomies. Nonsurgical options are ineffective after femoral head collapse, and treatment options become more invasive. Bone-preserving techniques utilized for post-collapse AVN include vascularized fibula grafts and osteotomies, but their results are unpredictable. The ultimate salvage options include hip resurfacing, bipolar

Original languageEnglish (US)
Title of host publicationHip Arthroscopy and Hip Joint Preservation Surgery
PublisherSpringer New York
Pages1038-1048
Number of pages11
ISBN (Electronic)9781461469650
ISBN (Print)9781461469643
DOIs
StatePublished - Jan 1 2015

Fingerprint

Hip
Thigh
Necrosis
Osteotomy
Decompression
Stanozolol
Post and Core Technique
Femur Head Necrosis
Bone Substitutes
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Fibula
Diphosphonates
Blood Vessels
Therapeutics
Bone Marrow
Transplants
Bone and Bones
Injections

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Houdek, M. T., Martin, J. R., & Sierra, R. J. (2015). Hip avascular necrosis: Overview. In Hip Arthroscopy and Hip Joint Preservation Surgery (pp. 1038-1048). Springer New York. https://doi.org/10.1007/978-1-4614-6965-0_92

Hip avascular necrosis : Overview. / Houdek, Matthew T.; Martin, John R.; Sierra, Rafael J.

Hip Arthroscopy and Hip Joint Preservation Surgery. Springer New York, 2015. p. 1038-1048.

Research output: Chapter in Book/Report/Conference proceedingChapter

Houdek, MT, Martin, JR & Sierra, RJ 2015, Hip avascular necrosis: Overview. in Hip Arthroscopy and Hip Joint Preservation Surgery. Springer New York, pp. 1038-1048. https://doi.org/10.1007/978-1-4614-6965-0_92
Houdek MT, Martin JR, Sierra RJ. Hip avascular necrosis: Overview. In Hip Arthroscopy and Hip Joint Preservation Surgery. Springer New York. 2015. p. 1038-1048 https://doi.org/10.1007/978-1-4614-6965-0_92
Houdek, Matthew T. ; Martin, John R. ; Sierra, Rafael J. / Hip avascular necrosis : Overview. Hip Arthroscopy and Hip Joint Preservation Surgery. Springer New York, 2015. pp. 1038-1048
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