Highlights in clinical autonomic neurosciences: Brain volume and autonomic regulation

William P. Cheshire

doi:10.1016/j.autneu.2014.05.001

Highlights in clinical autonomic neurosciences: Brain volume and autonomic regulation

William P. Cheshire

Neurology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Advances in volumetric magnetic resonance imaging (MRI) technology are beginning to provide structural correlates to functional dysautonomic syndromes in the brain. This paper highlights several interesting recent discoveries in which measurable variations in general or regional subcortical or cortical brain volume corresponded to changes in blood pressure or heart rate. Although these MRI findings currently lack diagnostic value in routine clinical practice, they may provide important clues to the pathophysiology of autonomic disorders and to links between autonomic and cognitive disorders. If validated by further studies, they also have potential implications for the management of orthostatic hypotension, particularly when combined with hypertension.

Original language	English (US)
Pages (from-to)	4-7
Number of pages	4
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	183
DOIs	https://doi.org/10.1016/j.autneu.2014.05.001
State	Published - Jul 2014

Keywords

Autonomic Nervous System Diseases
Bradycardia
Dementia
Hippocampus
Hypertension
Hypotension
Magnetic Resonance Imaging
Syncope

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1016/j.autneu.2014.05.001

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abstract = "Advances in volumetric magnetic resonance imaging (MRI) technology are beginning to provide structural correlates to functional dysautonomic syndromes in the brain. This paper highlights several interesting recent discoveries in which measurable variations in general or regional subcortical or cortical brain volume corresponded to changes in blood pressure or heart rate. Although these MRI findings currently lack diagnostic value in routine clinical practice, they may provide important clues to the pathophysiology of autonomic disorders and to links between autonomic and cognitive disorders. If validated by further studies, they also have potential implications for the management of orthostatic hypotension, particularly when combined with hypertension.",

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KW - Hippocampus

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KW - Hypotension

KW - Magnetic Resonance Imaging

KW - Syncope

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ER -

Highlights in clinical autonomic neurosciences: Brain volume and autonomic regulation

Abstract

Keywords

ASJC Scopus subject areas

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