High-Intensity Interval Training in Cardiac Rehabilitation: Impact on Fat Mass in Patients With Myocardial Infarction

Yaoshan Dun, Randal J. Thomas, Jose R. Medina-Inojosa, Ray W. Squires, Hsuhang Huang, Joshua R. Smith, Suixin Liu, Thomas P Olson

Research output: Contribution to journalArticle

Abstract

Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.

Original languageEnglish (US)
Pages (from-to)1718-1730
Number of pages13
JournalMayo Clinic proceedings
Volume94
Issue number9
DOIs
StatePublished - Sep 1 2019

Fingerprint

Fats
Myocardial Infarction
Abdominal Fat
Exercise
Adipose Tissue
Body Mass Index
X-Rays
Body Fat Distribution
Lipids
High-Intensity Interval Training
Cardiac Rehabilitation
Waist Circumference
LDL Cholesterol
Energy Metabolism
Triglycerides
Cholesterol
Body Weight

ASJC Scopus subject areas

  • Medicine(all)

Cite this

High-Intensity Interval Training in Cardiac Rehabilitation : Impact on Fat Mass in Patients With Myocardial Infarction. / Dun, Yaoshan; Thomas, Randal J.; Medina-Inojosa, Jose R.; Squires, Ray W.; Huang, Hsuhang; Smith, Joshua R.; Liu, Suixin; Olson, Thomas P.

In: Mayo Clinic proceedings, Vol. 94, No. 9, 01.09.2019, p. 1718-1730.

Research output: Contribution to journalArticle

Dun, Yaoshan ; Thomas, Randal J. ; Medina-Inojosa, Jose R. ; Squires, Ray W. ; Huang, Hsuhang ; Smith, Joshua R. ; Liu, Suixin ; Olson, Thomas P. / High-Intensity Interval Training in Cardiac Rehabilitation : Impact on Fat Mass in Patients With Myocardial Infarction. In: Mayo Clinic proceedings. 2019 ; Vol. 94, No. 9. pp. 1718-1730.
@article{2cc565a72c7641a1993843f9804f82b0,
title = "High-Intensity Interval Training in Cardiac Rehabilitation: Impact on Fat Mass in Patients With Myocardial Infarction",
abstract = "Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7{\%} [24 of 90 patients in the HIIT group] vs 26.7{\%} [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.",
author = "Yaoshan Dun and Thomas, {Randal J.} and Medina-Inojosa, {Jose R.} and Squires, {Ray W.} and Hsuhang Huang and Smith, {Joshua R.} and Suixin Liu and Olson, {Thomas P}",
year = "2019",
month = "9",
day = "1",
doi = "10.1016/j.mayocp.2019.04.033",
language = "English (US)",
volume = "94",
pages = "1718--1730",
journal = "Mayo Clinic Proceedings",
issn = "0025-6196",
publisher = "Elsevier Science",
number = "9",

}

TY - JOUR

T1 - High-Intensity Interval Training in Cardiac Rehabilitation

T2 - Impact on Fat Mass in Patients With Myocardial Infarction

AU - Dun, Yaoshan

AU - Thomas, Randal J.

AU - Medina-Inojosa, Jose R.

AU - Squires, Ray W.

AU - Huang, Hsuhang

AU - Smith, Joshua R.

AU - Liu, Suixin

AU - Olson, Thomas P

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.

AB - Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.

UR - http://www.scopus.com/inward/record.url?scp=85071453879&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071453879&partnerID=8YFLogxK

U2 - 10.1016/j.mayocp.2019.04.033

DO - 10.1016/j.mayocp.2019.04.033

M3 - Article

C2 - 31486378

AN - SCOPUS:85071453879

VL - 94

SP - 1718

EP - 1730

JO - Mayo Clinic Proceedings

JF - Mayo Clinic Proceedings

SN - 0025-6196

IS - 9

ER -