TY - JOUR
T1 - High-Intensity Interval Training in Cardiac Rehabilitation
T2 - Impact on Fat Mass in Patients With Myocardial Infarction
AU - Dun, Yaoshan
AU - Thomas, Randal J.
AU - Medina-Inojosa, Jose R.
AU - Squires, Ray W.
AU - Huang, Hsuhang
AU - Smith, Joshua R.
AU - Liu, Suixin
AU - Olson, Thomas P.
N1 - Funding Information:
Grant Support: This study was supported in part by grant HL-126638 from the US National Institutes of Health (T.P.O.) and grant [2012] 1521 from the Hunan Development and Reform Commission Foundation of China. Grant Support: This study was supported in part by grant HL-126638 from the US National Institutes of Health (T.P.O.) and grant [2012] 1521 from the Hunan Development and Reform Commission Foundation of China. We thank the patients and staff of the Mayo Clinic Cardiac Rehabilitation Program in Rochester, Minnesota, for their valuable contributions to the study. Grant Support: This study was supported in part by grant HL-126638 from the US National Institutes of Health (T.P.O.) and grant [2012] 1521 from the Hunan Development and Reform Commission Foundation of China.
Publisher Copyright:
© 2019 Mayo Foundation for Medical Education and Research
PY - 2019/9
Y1 - 2019/9
N2 - Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.
AB - Objective: To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR). Patients and Methods: We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures. Results: The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m2) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted. Conclusion: Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.
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U2 - 10.1016/j.mayocp.2019.04.033
DO - 10.1016/j.mayocp.2019.04.033
M3 - Article
C2 - 31486378
AN - SCOPUS:85071453879
SN - 0025-6196
VL - 94
SP - 1718
EP - 1730
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 9
ER -