Abstract
Background: To examine the effect of high-intensity interval training (HIIT) on metabolic syndrome (MetS) and body composition in cardiac rehabilitation (CR) patients with myocardial infarction (MI). Methods: We retrospectively screened 174 consecutive patients with MetS enrolled in CR following MI between 2015 and 2018. We included 56 patients who completed 36 CR sessions and pre-post dual-energy X-ray absorptiometry. Of these patients, 42 engaged in HIIT and 14 in moderate-intensity continuous training (MICT). HIIT included 4-8 intervals of high-intensity (30-60 s at RPE 15-17 [Borg 6-20]) and low-intensity (1-5 min at RPE < 14), and MICT included 20-45 min of exercise at RPE 12-14. MetS and body composition variables were compared between MICT and HIIT groups. Results: Compared to MICT, HIIT demonstrated greater reductions in MetS (relative risk = 0.5, 95% CI 0.33-0.75, P <.001), MetS z-score (- 3.6 ± 2.9 vs. - 0.8 ± 3.8, P <.001) and improved MetS components: waist circumference (- 3 ± 5 vs. 1 ± 5 cm, P =.01), fasting blood glucose (- 25.8 ± 34.8 vs. - 3.9 ± 25.8 mg/dl, P <.001), triglycerides (- 67.8 ± 86.7 vs. - 10.4 ± 105.3 mg/dl, P <.001), and diastolic blood pressure (- 7 ± 11 vs. 0 ± 13 mmHg, P =.001). HIIT group demonstrated greater reductions in body fat mass (- 2.1 ± 2.1 vs. 0 ± 2.2 kg, P =.002), with increased body lean mass (0.9 ± 1.9 vs. - 0.9 ± 3.2 kg, P =.01) than the MICT. After matching for exercise energy expenditure, HIIT-induced improvements persisted for MetS z-score (P <.001), MetS components (P <.05), body fat mass (P =.002), body fat (P =.01), and lean mass (P =.03). Conclusions: Our data suggest that, compared to MICT, supervised HIIT results in greater improvements in MetS and body composition in MI patients with MetS undergoing CR.
| Original language | English (US) |
|---|---|
| Article number | 104 |
| Journal | Cardiovascular Diabetology |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| State | Published - Aug 14 2019 |
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Keywords
- Body composition
- Cardiac rehabilitation
- High-intensity interval training
- Metabolic syndrome
- Myocardial infarction
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Cardiology and Cardiovascular Medicine
Cite this
High-intensity interval training improves metabolic syndrome and body composition in outpatient cardiac rehabilitation patients with myocardial infarction. / Dun, Yaoshan; Thomas, Randal J.; Smith, Joshua R.; Medina-Inojosa, Jose R.; Squires, Ray W.; Bonikowske, Amanda R.; Huang, Hsuhang; Liu, Suixin; Olson, Thomas P.
In: Cardiovascular Diabetology, Vol. 18, No. 1, 104, 14.08.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High-intensity interval training improves metabolic syndrome and body composition in outpatient cardiac rehabilitation patients with myocardial infarction
AU - Dun, Yaoshan
AU - Thomas, Randal J.
AU - Smith, Joshua R.
AU - Medina-Inojosa, Jose R.
AU - Squires, Ray W.
AU - Bonikowske, Amanda R.
AU - Huang, Hsuhang
AU - Liu, Suixin
AU - Olson, Thomas P
PY - 2019/8/14
Y1 - 2019/8/14
N2 - Background: To examine the effect of high-intensity interval training (HIIT) on metabolic syndrome (MetS) and body composition in cardiac rehabilitation (CR) patients with myocardial infarction (MI). Methods: We retrospectively screened 174 consecutive patients with MetS enrolled in CR following MI between 2015 and 2018. We included 56 patients who completed 36 CR sessions and pre-post dual-energy X-ray absorptiometry. Of these patients, 42 engaged in HIIT and 14 in moderate-intensity continuous training (MICT). HIIT included 4-8 intervals of high-intensity (30-60 s at RPE 15-17 [Borg 6-20]) and low-intensity (1-5 min at RPE < 14), and MICT included 20-45 min of exercise at RPE 12-14. MetS and body composition variables were compared between MICT and HIIT groups. Results: Compared to MICT, HIIT demonstrated greater reductions in MetS (relative risk = 0.5, 95% CI 0.33-0.75, P <.001), MetS z-score (- 3.6 ± 2.9 vs. - 0.8 ± 3.8, P <.001) and improved MetS components: waist circumference (- 3 ± 5 vs. 1 ± 5 cm, P =.01), fasting blood glucose (- 25.8 ± 34.8 vs. - 3.9 ± 25.8 mg/dl, P <.001), triglycerides (- 67.8 ± 86.7 vs. - 10.4 ± 105.3 mg/dl, P <.001), and diastolic blood pressure (- 7 ± 11 vs. 0 ± 13 mmHg, P =.001). HIIT group demonstrated greater reductions in body fat mass (- 2.1 ± 2.1 vs. 0 ± 2.2 kg, P =.002), with increased body lean mass (0.9 ± 1.9 vs. - 0.9 ± 3.2 kg, P =.01) than the MICT. After matching for exercise energy expenditure, HIIT-induced improvements persisted for MetS z-score (P <.001), MetS components (P <.05), body fat mass (P =.002), body fat (P =.01), and lean mass (P =.03). Conclusions: Our data suggest that, compared to MICT, supervised HIIT results in greater improvements in MetS and body composition in MI patients with MetS undergoing CR.
AB - Background: To examine the effect of high-intensity interval training (HIIT) on metabolic syndrome (MetS) and body composition in cardiac rehabilitation (CR) patients with myocardial infarction (MI). Methods: We retrospectively screened 174 consecutive patients with MetS enrolled in CR following MI between 2015 and 2018. We included 56 patients who completed 36 CR sessions and pre-post dual-energy X-ray absorptiometry. Of these patients, 42 engaged in HIIT and 14 in moderate-intensity continuous training (MICT). HIIT included 4-8 intervals of high-intensity (30-60 s at RPE 15-17 [Borg 6-20]) and low-intensity (1-5 min at RPE < 14), and MICT included 20-45 min of exercise at RPE 12-14. MetS and body composition variables were compared between MICT and HIIT groups. Results: Compared to MICT, HIIT demonstrated greater reductions in MetS (relative risk = 0.5, 95% CI 0.33-0.75, P <.001), MetS z-score (- 3.6 ± 2.9 vs. - 0.8 ± 3.8, P <.001) and improved MetS components: waist circumference (- 3 ± 5 vs. 1 ± 5 cm, P =.01), fasting blood glucose (- 25.8 ± 34.8 vs. - 3.9 ± 25.8 mg/dl, P <.001), triglycerides (- 67.8 ± 86.7 vs. - 10.4 ± 105.3 mg/dl, P <.001), and diastolic blood pressure (- 7 ± 11 vs. 0 ± 13 mmHg, P =.001). HIIT group demonstrated greater reductions in body fat mass (- 2.1 ± 2.1 vs. 0 ± 2.2 kg, P =.002), with increased body lean mass (0.9 ± 1.9 vs. - 0.9 ± 3.2 kg, P =.01) than the MICT. After matching for exercise energy expenditure, HIIT-induced improvements persisted for MetS z-score (P <.001), MetS components (P <.05), body fat mass (P =.002), body fat (P =.01), and lean mass (P =.03). Conclusions: Our data suggest that, compared to MICT, supervised HIIT results in greater improvements in MetS and body composition in MI patients with MetS undergoing CR.
KW - Body composition
KW - Cardiac rehabilitation
KW - High-intensity interval training
KW - Metabolic syndrome
KW - Myocardial infarction
UR - http://www.scopus.com/inward/record.url?scp=85071138129&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071138129&partnerID=8YFLogxK
U2 - 10.1186/s12933-019-0907-0
DO - 10.1186/s12933-019-0907-0
M3 - Article
C2 - 31412869
AN - SCOPUS:85071138129
VL - 18
JO - Cardiovascular Diabetology
JF - Cardiovascular Diabetology
SN - 1475-2840
IS - 1
M1 - 104
ER -